Integrating neural cultures developed through synthetic biology methods with digital
computing has enabled the early development of Synthetic Biological Intelligence (SBI) …

Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of
electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the …

Biological computing (or biocomputing) offers potential advantages over silicon-based
computing in terms of faster decision-making, continuous learning during tasks, and greater …

Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

Spike sorting is a crucial step in electrophysiological studies of neuronal activity. While many
spike sorting packages are available, there is little consensus about which are most …

Recording from a large neuronal population of neurons is a crucial challenge to unravel how
information is processed by the brain. In this review, we highlight the recent advances made …

大数据时代, 数据爆炸式的增长, 数据获取变得更容易的同时数据缺失现象也更加普遍.
数据的缺失极大地降低了数据的实用性. 数据缺失问题的处理成为大数据处理的热点研究课题 …

The synchronous activity of neuronal networks is considered crucial for brain function.
However, the interaction between single-neuron activity and network-wide activity remains …

Modern recording technologies now enable simultaneous recording from large numbers of
neurons. This has driven the development of new statistical models for analyzing and …

With their 'all-or-none'action potential responses, single neurons (or units) are accepted as
the basic computational unit of the brain. There is extensive animal literature to support the …