Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology at the earliest stage of some neurodegenerative disorders, but do not have the scalability …
X Deng, M Li, S Deng, L Wang - Medical & Biological Engineering & …, 2022 - Springer
Microarray gene expression data are often accompanied by a large number of genes and a small number of samples. However, only a few of these genes are relevant to cancer …
Huntington's disease is an autosomal-dominant, progressive neurodegenerative disorder with a distinct phenotype, including chorea and dystonia, incoordination, cognitive decline …
C Zuccato, M Valenza, E Cattaneo - Physiological reviews, 2010 - journals.physiology.org
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the gene encoding for huntingtin protein. A lot has been learned about this …
MM Khamis, DJ Adamko… - Mass spectrometry …, 2017 - Wiley Online Library
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐ invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
R Johnson - Neurobiology of disease, 2012 - Elsevier
Neurodegeneration in the brains of Huntington's disease patients is accompanied by widespread changes in gene regulatory networks. Recent studies have found that these …
The biologic underpinnings of posttraumatic stress disorder (PTSD) have not been fully elucidated. Previous work suggests that alterations in the immune system are characteristic …
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting motor neurons. Disease onset and progression are variable, with survival ranging from months to …
JMM van der Burg, M Björkqvist, P Brundin - The Lancet Neurology, 2009 - thelancet.com
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by a polyglutamine stretch in the huntingtin protein. Today, more than 15 years after the genetic …