Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials

L Yu, G Zhu, Z Zhang, Y Yu, L Zeng, Z Xu… - Journal of …, 2023 - Springer
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …

A review on biomedical application of polysaccharide-based hydrogels with a focus on drug delivery systems

B Farasati Far, MR Naimi-Jamal, M Safaei, K Zarei… - Polymers, 2022 - mdpi.com
Over the last years of research on drug delivery systems (DDSs), natural polymer-based
hydrogels have shown many scientific advances due to their intrinsic properties and a wide …

Synthesis and characterization of dual light/temperature-responsive supramolecular injectable hydrogel based on host-guest interaction between azobenzene and …

B Pourbadiei, SY Adlsadabad, N Rahbariasr… - Carbohydrate …, 2023 - Elsevier
Injectable stimuli-responsive hydrogels could offer an opportunity for local administration at
the tumor site and a sustained drug release. In this paper, a copolymer of azobenzene …

Bioactive delivery systems based on starch and its derivatives: Assembly and application at different structural levels

X Liang, L Chen, DJ McClements, X Peng, Z Xu… - Food Chemistry, 2024 - Elsevier
Starch and modified starch, spanning various structural levels, are comprehensively
reviewed, with a special emphasis on the advancement of starch and its derivative-based …

Microbiota-sensitive drug delivery systems based on natural polysaccharides for colon targeting

H Azehaf, Y Benzine, M Tagzirt, M Skiba, Y Karrout - Drug Discovery Today, 2023 - Elsevier
Highlights•Overview of colonic drug delivery systems.•Potential for local and systemic
delivery.•Key focus on metabolic activity of the colonic microbiota.•Challenges of microbiota …

Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment

X Ge, H Wen, Y Fei, R Xue, Z Cheng, Y Li, K Cai, L Li… - Biomaterials, 2023 - Elsevier
Hydrogels are a class of biocompatible materials with versatile functions that have been
increasing explored for the localized treatment of ulcerative colitis (UC), but various …

In-vitro evaluation of the 5-fluorouracil loaded GQDs@ Bio-MOF capped with starch biopolymer for improved colon-specific delivery

Y Hassanpouraghdam, M Pooresmaeil… - International Journal of …, 2022 - Elsevier
Herein, for the first time, the photoluminescent graphene quantum dots@ Bio-metal organic
framework (GQDs@ Bio-MOF) nanohybrid was prepared. BET analysis obtained the …

Plant polysaccharides in engineered pharmaceutical gels

JO Bahú, LRM de Andrade, R de Melo Barbosa… - Bioengineering, 2022 - mdpi.com
Hydrogels are a great ally in the pharmaceutical and biomedical areas. They have a three-
dimensional polymeric structure that allows the swelling of aqueous fluids, acting as an …

The function of natural polysaccharides in the treatment of ulcerative colitis

Y Guo, Y Li, Q Cao, L Ye, J Wang, M Guo - Frontiers in Pharmacology, 2022 - frontiersin.org
Ulcerative colitis (UC) is an inflammatory bowel disease that is persistent and nonspecific.
There are several medications available for the treatment of UC. However, conventional UC …

Strategies and opportunities of micro/nano delivery systems for targeted therapy of ulcerative colitis: Focus on underlying mechanisms and future perspectives

Z Liu, H Liu, J Cheng, H Wang, Y Yang, J Ye… - Chinese Chemical …, 2024 - Elsevier
Ulcerative colitis (UC) is a common progressive inflammatory disease whose incidence has
increased rapidly in recent years, and can develop into colorectal cancer in severe cases …