MK-801 and cognitive functions: Investigating the behavioral effects of a non-competitive NMDA receptor antagonist

A Janus, K Lustyk, K Pytka - Psychopharmacology, 2023 - Springer
Abstract Rationale MK-801 (dizocilpine) is a non-competitive NMDA receptor antagonist
originally explored for anticonvulsant potential. Despite its original purpose, its amnestic …

Photobiomodulation in the aging brain: a systematic review from animal models to humans

L Rodríguez-Fernández, C Zorzo, JL Arias - GeroScience, 2024 - Springer
Aging is a multifactorial biological process that may be associated with cognitive decline.
Photobiomodulation (PBM) is a non-pharmacological therapy that shows promising results …

Sevoflurane postconditioning mitigates neuronal hypoxic-ischemic injury via regulating reactive astrocytic STAT3 protein modification

Y Jia, Y Song, H Xue, X Li, Y Zhang, S Fan… - Chemico-Biological …, 2025 - Elsevier
Astrocyte activation plays a pivotal role in accelerating the cascade of neuroinflammation
associated with the development of hypoxic-ischemic brain injury. This study aimed to …

Voluntary exercise during puberty promotes spatial memory and hippocampal DG/CA3 synaptic transmission in mice

C Wan, X Song, Z Zhang, W Hu, Y Chen, W Sun… - Cerebral …, 2024 - academic.oup.com
Physical exercise has been shown to have an impact on memory and hippocampal function
across different age groups. Nevertheless, the influence and mechanisms underlying how …

[HTML][HTML] Learning and metabolic brain differences between juvenile male and female rats in the execution of different training regimes of a spatial memory task

A Gutiérrez-Menéndez, M Méndez, JL Arias - Physiology & Behavior, 2023 - Elsevier
Spatial memory is responsible for encoding spatial information to form a path, storing this
mental representation, and evaluating and recovering spatial configurations to find a target …

Long-term voluntary running improves cognitive ability in developing mice by modulating the cholinergic system, antioxidant ability, and BDNF/PI3K/Akt/CREB …

C Wan, L Shi, Y Lai, Z Wu, M Zou, Z Liu, W Meng… - Neuroscience …, 2024 - Elsevier
Moderate physical exercise has positive effects on memory. The present study aimed to
investigate the impact of long-term exercise on spatial memory in developing mice, as well …

[HTML][HTML] The removal and addition of cues does not impair spatial retrieval and leads to a different metabolic activity of the limbic network in female rats

C Zorzo, JL Arias, M Méndez - Brain research bulletin, 2022 - Elsevier
The retrieval of spatial memories does not always occur in an environment with the same
stimuli configuration where the memory was first formed. However, re-exposure to a partial …