Multiple roles of Apolipoprotein E4 in oxidative lipid metabolism and Ferroptosis during the pathogenesis of Alzheimer's disease

P Faraji, H Kühn, S Ahmadian - Journal of Molecular Neuroscience, 2024 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease worldwide and
has a great socio-economic impact. Modified oxidative lipid metabolism and dysregulated …

Recognizing Alzheimer's disease from perspective of oligodendrocytes: Phenomena or pathogenesis?

J Wang, Y Zhen, J Yang, S Yang… - CNS Neuroscience & …, 2024 - Wiley Online Library
Background Accumulation of amyloid beta, tau hyperphosphorylation, and microglia
activation are the three highly acknowledged pathological factors of Alzheimer's disease …

[HTML][HTML] Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for …

NF Alahmady, FM Alkhulaifi, MA Momenah… - Saudi Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) causes dementia among older adults, increasing the global
burden of dementia. Therefore, this study investigates the potential neuroprotective …

Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease

S Xu, L Kong, L Li, C Wang, J Gu, H Luo… - Biochimica et Biophysica …, 2024 - Elsevier
Oxidative stress-mediated activation of inflammasome has a significant effect on the
pathogenesis of nonalcoholic fatty liver disease (NAFLD). Farnesoid X receptor (NR1H4 …

[PDF][PDF] Role of Apolipoprotein E in Alzheimer's Disease Pathogenesis, Prognosis and Treatment

AB Reiss, M Housny, S Gulkarov, T Hossain… - Discovery …, 2024 - researchgate.net
Alzheimer's disease (AD) is an incurable and progressive neurodegenerative disease with
increasing prevalence worldwide. Previous trials of anti-amyloid and anti-tau …

[HTML][HTML] Association between Alzheimer's disease and metabolic syndrome: Unveiling the role of dyslipidemia mechanisms

C Yue, Y Fu, Y Zhao, Y Ou, Y Sun, L Tan - Brain Network Disorders, 2024 - Elsevier
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
progressive cognitive decline and memory problems. With a growing elderly population and …