2021 American College of Rheumatology guideline for the treatment of juvenile idiopathic arthritis: recommendations for nonpharmacologic therapies, medication …

KB Onel, DB Horton, DJ Lovell, S Shenoi… - Arthritis care & …, 2022 - Wiley Online Library
Objective To provide recommendations for the management of juvenile idiopathic arthritis
(JIA) with a focus on nonpharmacologic therapies, medication monitoring, immunizations …

Polypharmacy: a healthcare conundrum with a pharmacogenetic solution

CN Sharp, MW Linder, R Valdes Jr - Critical reviews in clinical …, 2020 - Taylor & Francis
The use of multiple medications is growing at an alarming rate with some reports
documenting an average of 12–22 prescriptions being used by individuals≥ 50 years of …

Complexity of medication regimens for children with neurological impairment

JA Feinstein, H Friedman, LE Orth… - JAMA network …, 2021 - jamanetwork.com
Importance Parents of children with severe neurological impairment (SNI) manage complex
medication regimens (CMRs) at home, and clinicians can help support parents and simplify …

Prevalence and age structure of polypharmacy in Poland: results of the analysis of the national real-world database of 38 million citizens

P Kardas, F Urbański, A Lichwierowicz… - Frontiers in …, 2021 - frontiersin.org
Introduction: Polypharmacy is a risk factor for adverse health outcomes, higher use of
medical services and additional costs. The problem has gained attention as a consequence …

Pharmacogenetic profiling via genome sequencing in children with medical complexity

A Pan, S Scodellaro, T Khan, I Ushcatz, W Wu… - Pediatric …, 2023 - nature.com
Background Children with medical complexity (CMC) are a priority pediatric population, with
high resource use and associated costs. Genome-wide sequencing is increasingly …

Effects of the number of drugs used on the prevalence of adverse drug reactions in children

M Sugioka, T Tachi, T Mizui, A Koyama, A Murayama… - Scientific Reports, 2020 - nature.com
In pediatric individuals, polypharmacy would increase the prevalence of adverse drug
reactions (ADRs). However, there is no report on the ADR increase adjusted for the …

High-level psychotropic polypharmacy: a retrospective comparison of children in foster care to their peers on Medicaid

DW Davis, WD Lohr, Y Feygin, L Creel, K Jawad… - BMC psychiatry, 2021 - Springer
Background The use of antipsychotic medication and psychotropic polypharmacy has
increased in the United States over the last two decades especially for children from low …

Drug safety in translational paediatric research: Practical points to consider for paediatric safety profiling and protocol development: A scoping review

B Aurich, E Jacqz-Aigrain - Pharmaceutics, 2021 - mdpi.com
Translational paediatric drug development includes the exchange between basic, clinical
and population-based research to improve the health of children. This includes the …

National prescribing rates and polypharmacy for children and young people in New Zealand with and without autism spectrum disorder

N Bowden, H Thabrew, J Kokaua, R Braund - Research in autism spectrum …, 2020 - Elsevier
Background International data and guidance on prescribing for children and young people
with autism spectrum disorder (ASD) are limited. National administrative datasets such as …

Use of chronic prescription medications and prevalence of polypharmacy in survivors of childhood cancer

CLY Ewig, YM Cheng, HS Li, JCL Wong… - Frontiers in …, 2021 - frontiersin.org
Background As survivors of childhood cancer age, development of cancer treatment-related
chronic health conditions often occur. This study aimed to describe the pattern of chronic …