Cross-species RNA-seq for deciphering host–microbe interactions
AJ Westermann, J Vogel - Nature Reviews Genetics, 2021 - nature.com
The human body is constantly exposed to microorganisms, which entails manifold
interactions between human cells and diverse commensal or pathogenic bacteria. The …
interactions between human cells and diverse commensal or pathogenic bacteria. The …
[HTML][HTML] Novel insights into host-pathogen interactions of large yellow croakers (Larimichthys crocea) and pathogenic bacterium Pseudomonas plecoglossicida using …
Y Tang, G Xin, LM Zhao, LX Huang, YX Qin… - Zoological …, 2020 - ncbi.nlm.nih.gov
Host-pathogen interactions are highly complex, involving large dynamic changes in gene
expression during infection. These interactions are fundamental to understanding anti …
expression during infection. These interactions are fundamental to understanding anti …
An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease
Streptococcus pneumoniae (Spn) colonizes the nasopharynx and can cause pneumonia.
From the lungs it spreads to the bloodstream and causes organ damage. We characterized …
From the lungs it spreads to the bloodstream and causes organ damage. We characterized …
Look Who's Talking: Host and Pathogen Drivers of Staphylococcus epidermidis Virulence in Neonatal Sepsis
Preterm infants are at increased risk for invasive neonatal bacterial infections. S.
epidermidis, a ubiquitous skin commensal, is a major cause of late-onset neonatal sepsis …
epidermidis, a ubiquitous skin commensal, is a major cause of late-onset neonatal sepsis …
Streptococcus pneumoniae epidemiology, pathogenesis and control
AR Narciso, R Dookie, P Nannapaneni… - Nature Reviews …, 2024 - nature.com
Infections caused by Streptococcus pneumoniae (also known as pneumococci) pose a
threat to human health. Pneumococcal infections are the most common cause of milder …
threat to human health. Pneumococcal infections are the most common cause of milder …
Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq
KK Jim, R Aprianto, R Koning, A Domenech… - Cell reports, 2022 - cell.com
Pneumolysin is a major virulence factor of Streptococcus pneumoniae that plays a key role
in interaction with the host during invasive disease. How pneumolysin influences these …
in interaction with the host during invasive disease. How pneumolysin influences these …
Streptococcus pneumoniae rapidly translocate from the nasopharynx through the cribriform plate to invade the outer meninges
T Audshasai, JA Coles, S Panagiotou, S Khandaker… - Mbio, 2022 - Am Soc Microbiol
The entry routes and translocation mechanisms of microorganisms or particulate materials
into the central nervous system remain obscure We report here that Streptococcus …
into the central nervous system remain obscure We report here that Streptococcus …
Tissue specific dual RNA-seq defines host–parasite interplay in murine visceral leishmaniasis caused by leishmania donovani and leishmania infantum
S Forrester, A Goundry, BT Dias… - Microbiology …, 2022 - Am Soc Microbiol
Visceral leishmaniasis is associated with hepato-splenomegaly and altered immune and
hematological parameters in both preclinical animal models and humans. We studied …
hematological parameters in both preclinical animal models and humans. We studied …
Time-resolved RNA-seq analysis to unravel the in vivo competence induction by Streptococcus pneumoniae during pneumonia-derived sepsis
Competence development in Streptococcus pneumoniae (pneumococcus) is tightly
intertwined with virulence. In addition to genes encoding genetic transformation machinery …
intertwined with virulence. In addition to genes encoding genetic transformation machinery …