The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …

TGF-β plays a prominent role as an inducer of epithelial-mesenchymal transitions (EMTs)
during development and wound healing and in disease conditions such as fibrosis and …

Abstract Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal
features from epithelial cells, occur during some biological processes and are classified into …

The epithelial-to-mesenchymal transition (EMT) is frequently co-opted by cancer cells to
enhance migratory and invasive cell traits. It is a key contributor to heterogeneity …

It is well established that multifactorial drug resistance hinders successful cancer treatment.
Tumor cell interactions with the tumor microenvironment (TME) are crucial in epithelial …

Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …

The cell-biological program termed the epithelial-to-mesenchymal transition (EMT) plays an
important role in both development and cancer progression. Depending on the contextual …

The success of anticancer therapy is usually limited by the development of drug resistance.
Such acquired resistance is driven, in part, by intratumoural heterogeneity—that is, the …

Cancer metastasis is no longer viewed as a linear cascade of events but rather as a series
of concurrent, partially overlapping processes, as successfully metastasizing cells assume …

Our traditional understanding of phenotypic plasticity in adult somatic cells comprises
dedifferentiation and transdifferentiation in the context of tissue regeneration or wound …