REFLECTIONS ON THE COMPLEX HISTORY OF THE CONCEPT OF CLOZAPINE-INDUCED
INFLAMMATION DURING TITRATION Page 1 411 Psychiatria Danubina, 2022; Vol. 34, No. 3 …

Clozapine is an effective antipsychotic medication used for treatment‐resistant
schizophrenia. However, it is underutilized due to rigorous hematologic monitoring …

Background Pharmacovigilance studies indicate clozapine history is marked by adverse
drug reactions (ADRs). Objective In a 2021 article, the United Kingdom (UK) had> 90% of …

Background The literature has paid very little attention to pericarditis, pericardial effusion
and pancreatitis during clozapine treatment in children and adolescents. Methods Cases of …

Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS)
syndrome is a rare adverse reaction. We aimed to screen a large pharmacovigilance …

We read with interest Gilbert Honigfeld's article entitled “Clozapine in treatment-resistant
schizophrenia: Who designed that famous US clinical trial?”(Honigfeld, 2023) published in …

The current literature globally highlights the efficacy of Clozapine in several psychiatric
disorders all over the world, with an FDA indication for reducing the risk of repeated suicidal …

Despite its enduring relevance as the single most effective and important evidence-based
treatment for schizophrenia, underutilization of clozapine remains considerable. To a …

Adverse drug reactions (ADRs) are considered rare or very rare events when they occur,
respectively, between≥ 1/10,000 and< 1/1,000, or< 1/10,000 drug expositions [1]. The …

Introduction Antipsychotic pharmacotherapy is considered a first-line treatment in
schizophrenia-related disorders and is associated with favorable prognosis and lower …