Background: Venous thromboembolism (VTE) complicates∼ 1.2 of every 1000 deliveries.
Despite these low absolute risks, pregnancy-associated VTE is a leading cause of maternal …

Objective To provide evidence to support updated guidelines for the management of
pregnant women with hereditary thrombophilia in order to reduce the risk of a first venous …

Genetic predispositions to venous thromboembolism (VTE) are relatively frequent in the
general population and comprise a heterogeneous group of disorders. Whereas the most …

Antithrombin (AT) deficiency is a high-risk thrombophilia and a rare condition. Despite full
anticoagulation during pregnancy and the postpartum period, women with AT deficiency …

Background Inherited quantitative (type I) deficiency of plasma antithrombin is associated
with a high risk of venous thromboembolism, which further increases in pregnancy. Inherited …

Purpose of review This manuscript addresses the risks for venous thromboembolism (VTE)
during pregnancy and the associated challenges of both diagnosis and treatment. Recent …

Hemostasis is a dynamic balance between coagulation, anticoagulation, and fibrinolysis.
The coagulation system plays an important role in body homeostasis by preventing …

The association between heritability of venous thromboembolism (VTE) and thrombophilia
was first reported clinically in 1956, later followed by the first description of a congenital …

Deficiency of antithrombin (AT; antithrombin III) can be inherited or acquired; it is defined as
an AT activity level that is consistently less than 80 percent of normal (or the lower limit of the …

Even though venous thromboembolism is a leading cause of maternal mortality in high-
income countries, there are limited high-quality data to assist clinicians with the …