Hypertension affects a significant proportion of the adult and aging population and
represents an important risk factor for vascular cognitive impairment and late-life dementia …

Anxiety is more common in patients with hypertension, and these two conditions frequently
coexist. Recently, more emphasis has been placed on determining etiology in patients with …

A large interventional trial, the Systolic Blood Pressure Intervention Trial sub-study termed
Memory and Cognition in Decreased Hypertension (SPRINT-MIND), found reduced risk of …

Cerebral blood flow (CBF) decreases across the adult lifespan; however, more studies are
needed to understand the underlying mechanisms. This study measured CBF and …

Dementia affects almost 50 million adults worldwide, and remains a major cause of death
and disability. Hypertension is a leading risk factor for dementia, including Alzheimer …

Dynamic cerebral autoregulation (dCA) is a key mechanism that regulates cerebral blood
flow (CBF) in response to transient changes in blood pressure (BP). Impairment of dCA …

Elevated blood pressure is a well-established risk factor for age-related cognitive decline.
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …

Aging is accompanied by a decrease in cerebral blood flow (CBF), especially in the
presence of preclinical cognitive decline. The role of cerebrovascular physiology including …

This study evaluated the association between systemic arterial blood pressure and cerebral
perfusion in 740 participants of the UK's largest tri-ethnic study with measurements of …

Introduction The true global burden of vascular cognitive impairment (VCI) is unknown.
Reducing risk factors for stroke and cardiovascular disease would inevitably curtail VCI …