5-HT3 receptor antagonists, first introduced to the market in the mid-1980s, are proven efficient agents to counteract chemotherapy-induced emesis. Nonetheless, recent …
VCC Capibaribe… - Journal of Pharmacy …, 2019 - academic.oup.com
Objectives Based on this, the central therapeutic effects of thymol were verified in the neurotrophic pathway. Methods Female swiss mice were divided into four groups: control …
GR Villas-Boas, SN Lavorato, MM Paes… - Pharmaceuticals, 2021 - mdpi.com
Serotonin (5-HT) receptors are found throughout central and peripheral nervous systems, mainly in brain regions involved in the neurobiology of anxiety and depression. 5-HT …
JK Díaz-Cantón, MA Torres-Ramos… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Litsea glaucescens K.(Lauraceae) is a small tree from the Mexican and Central American temperate forests, named as “Laurel”. Its aromatic leaves are …
Abstract 5HT 3 receptors (5HT3Rs) have long been identified as a potential target for antidepressants. Several studies have reported that antagonism of 5HT3Rs produces …
L Orsolini, C Tomasetti, A Valchera… - CNS & Neurological …, 2017 - ingentaconnect.com
Background: Vortioxetine (VRX) is a multimodal antidepressant that acts as serotonin (5HT) transporter inhibitor as well as 5HT3A and 5HT7 receptors antagonist, 5HT1A and 5HT1B …
Previous work from this laboratory hypothesized that the multimodal antidepressant vortioxetine enhances cognitive function through a complex mechanism, using serotonergic …
DJ David, AM Gardier - L'encéphale, 2016 - Elsevier
Résumé Si la sérotonine ou 5-hydroxytryptamine (5-HT) est peut-être plus connue pour son rôle dans la régulation de l'humeur, il ne faut pas oublier qu'elle participe à la régulation de …
V Martin, A Riffaud, T Marday… - British Journal of …, 2017 - Wiley Online Library
Background and Purpose It has recently been suggested that 5‐HT3 receptor blockade enhances the efficacy of selective 5‐HT (serotonin) reuptake inhibitor (SSRI) …