Disruption of cerebral iron regulation appears to have a role in aging and in the
pathogenesis of various neurodegenerative disorders. Possible unfavorable impacts of iron …

Recent MRI advances allow depicting differences between the various subtypes of NBIA,
providing a useful analytical framework for clinicians. Standardization of protocols for image …

Purpose To evaluate the effect of resolution on iron content using quantitative susceptibility
mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in …

The visualization and identification of the deep cerebellar nuclei (DCN)(dentate [DN],
interposed [IN] and fastigial nuclei [FN]) are particularly challenging. We aimed to visualize …

Aims Aceruloplasminemia is an ultra-rare neurodegenerative disorder associated with
massive brain iron deposits, of which the molecular composition is unknown. We aimed to …

Background and purpose Aceruloplasminemia is an uncommon genetic disorder with
considerable diversity in clinical manifestations and tissue iron overload, whose underlying …

Aims Non-invasive measures of brain iron content would be of great benefit in
neurodegeneration with brain iron accumulation (NBIA) to serve as a biomarker for disease …

Aceruloplasminemia (ACP) is a rare disorder of iron overload resulting from ceruloplasmin
(CP) variants. Because of its rarity and heterogeneity, the diagnosis of ACP is often missed …

The association and underlying mechanisms between iron deposition and white matter
hyperintensity (WMH) remain unclear. In this study, quantitative susceptibility mapping …

Iron is essential to human survival. The biological role and trafficking of this trace essential
inorganic element which is also a potential toxin is constantly being researched and …