Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders

A Mata-Bermudez, R Trejo-Chávez… - Frontiers in …, 2024 - frontiersin.org
Traumatic brain injury (TBI) represents a public health issue with a high mortality rate and
severe neurological and psychiatric consequences. Mood and anxiety disorders are some of …

Simultaneous Mapping of Amino Neurotransmitters and Nucleoside Neuromodulators on Brain Tissue Sections by On-Tissue Chemoselective Derivatization and …

D Liu, X Liu, S Huang, X Shen, X Zhang… - Analytical …, 2023 - ACS Publications
Neurotransmitters (NTs) and neuromodulators (NMs) are two of the most important
neurochemicals in the brain, and their imbalances in specific brain regions are thought to …

The role of dorsolateral striatum in the effects of deep cerebellar stimulation-mediated motor recovery following ischemic stroke in rodents

HH Chan, ND Mathews, H Khanna, N Mandava… - Experimental …, 2024 - Elsevier
Despite great advances in acute care and rehabilitation, stroke remains the leading cause of
motor impairment in the industrialized world. We have developed a deep brain stimulation …

Treatment of cognitive and mood disorders secondary to traumatic brain injury by the association of bilateral occipital nerve stimulation and a combined protocol of …

T Caloc'h, E Le Saout, S Litaneur, A Suarez… - Frontiers in …, 2023 - frontiersin.org
Purpose Cognitive impairment secondary to traumatic brain injury (TBI) is difficult to treat
and usually results in severe disability. Method A 48-year-old man presented with chronic …

In-Hospital Amantadine Does Not Improve Outcomes After Severe Traumatic Brain Injury: An 11-Year Propensity-Matched Retrospective Analysis

JN Passman, NA Cleri, JR Saadon, N Naddaf… - World Neurosurgery, 2023 - Elsevier
Background Disruption of dopamine neurotransmission is associated with functional
impairment after severe traumatic brain injury (sTBI). This has prompted the study of …

Traumatic brain injury extending to the striatum alters autonomic thermoregulation and hypothalamic monoamines in recovering rats

A Verduzco-Mendoza, D Mota-Rojas… - Frontiers in …, 2023 - frontiersin.org
The brain cortex is the structure that is typically injured in traumatic brain injury (TBI) and is
anatomically connected with other brain regions, including the striatum and hypothalamus …

Sex-Specific and Traumatic Brain Injury Effects on Dopamine Receptor Expression in the Hippocampus

J Iannucci, K O'Neill, X Wang, S Mukherjee… - International Journal of …, 2023 - mdpi.com
Traumatic brain injury (TBI) is a major health concern. Each year, over 50 million individuals
worldwide suffer from TBI, and this leads to a number of acute and chronic health issues …

HIV-proteins-associated CNS neurotoxicity, their mediators, and alternative treatments

A Saro, Z Gao, PA Kambey, P Pielnaa… - Cellular and Molecular …, 2021 - Springer
Human immunodeficiency virus (HIV)-infected people's livelihoods are gradually being
prolonged with the use of combined antiretroviral therapy (ART). Conversely, despite viral …

[HTML][HTML] Severe Traumatic Brain Injury Outcomes in Patients with Premorbid Psychiatric Illness

JN Passman, NA Cleri, J Robertson, JR Saadon… - World Neurosurgery, 2025 - Elsevier
Objective Individuals with psychiatric illnesses (PIs) have increased rates of traumatic brain
injury (TBI). Nonetheless, the influence of underlying PI on TBI outcomes is poorly …

Traumatic brain injury, alone or with striatal hemorrhage-like extension, transiently decreases GABA and glutamate levels along motor deficits in the rat striatum: an in …

A Avila-Luna, R Cruz-Castro, A Verduzco-Mendoza… - Neuroscience …, 2025 - Elsevier
The cerebral cortex is connected to the striatum via the axons of the pyramidal glutamatergic
neurons, and this pathway is intimately involved in motor function. In the striatum …