Exploring diverse frontiers: Advancements of bioactive 4-aminoquinoline-based molecular hybrids in targeted therapeutics and beyond

L Ravindar, SA Hasbullah, KP Rakesh… - European Journal of …, 2024 - Elsevier
Amongst heterocyclic compounds, quinoline and its derivatives are advantaged scaffolds
that appear as a significant assembly motif for developing new drug entities. Aminoquinoline …

Design and synthesis of pyrano [2, 3-c] pyrazole-4-aminoquinoline hybrids as effective antimalarial compounds

R Lekkala, YH Ng, SR Feroz, NAZB Norazmi… - European Journal of …, 2024 - Elsevier
In this work, a series of nineteen novel pyrano [2, 3-c] pyrazole-4-aminoquinoline hybrids
were synthesized as potent antimalarial agents by covalently linking the scaffolds of 4 …