Virtual clinical trials in medical imaging: a review

E Abadi, WP Segars, BMW Tsui… - Journal of Medical …, 2020 - spiedigitallibrary.org
The accelerating complexity and variety of medical imaging devices and methods have
outpaced the ability to evaluate and optimize their design and clinical use. This is a …

Three-dimensional cardiac computational modelling: methods, features and applications

A Lopez-Perez, R Sebastian, JM Ferrero - Biomedical engineering online, 2015 - Springer
The combination of computational models and biophysical simulations can help to interpret
an array of experimental data and contribute to the understanding, diagnosis and treatment …

Multivariate mixture model for myocardial segmentation combining multi-source images

X Zhuang - IEEE transactions on pattern analysis and machine …, 2018 - ieeexplore.ieee.org
The author proposes a method for simultaneous registration and segmentation of multi-
source images, using the multivariate mixture model (MvMM) and maximum of log-likelihood …

Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function

M Fedele, A Quarteroni - International Journal for Numerical …, 2021 - Wiley Online Library
In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …

Linking statistical shape models and simulated function in the healthy adult human heart

C Rodero, M Strocchi, M Marciniak… - PLoS computational …, 2021 - journals.plos.org
Cardiac anatomy plays a crucial role in determining cardiac function. However, there is a
poor understanding of how specific and localised anatomical changes affect different …

A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion

W Bai, W Shi, A de Marvao, TJW Dawes… - Medical image …, 2015 - Elsevier
Atlases encode valuable anatomical and functional information from a population. In this
work, a bi-ventricular cardiac atlas was built from a unique data set, which consists of high …

A review of visualization techniques of post-mortem computed tomography data for forensic death investigations

LC Ebert, S Franckenberg, T Sieberth… - International journal of …, 2021 - Springer
Postmortem computed tomography (PMCT) is a standard image modality used in forensic
death investigations. Case-and audience-specific visualizations are vital for identifying …

[HTML][HTML] A bi-atrial statistical shape model for large-scale in silico studies of human atria: model development and application to ECG simulations

C Nagel, S Schuler, O Dössel, A Loewe - Medical Image Analysis, 2021 - Elsevier
Large-scale electrophysiological simulations to obtain electrocardiograms (ECG) carry the
potential to produce extensive datasets for training of machine learning classifiers to, eg …

Statistical shape modeling of the left ventricle: myocardial infarct classification challenge

A Suinesiaputra, P Ablin, X Alba… - IEEE journal of …, 2017 - ieeexplore.ieee.org
Statistical shape modeling is a powerful tool for visualizing and quantifying geometric and
functional patterns of the heart. After myocardial infarction (MI), the left ventricle typically …

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations

M Strocchi, CM Augustin, MAF Gsell, E Karabelas… - PloS one, 2020 - journals.plos.org
Computational models of the heart are increasingly being used in the development of
devices, patient diagnosis and therapy guidance. While software techniques have been …