Psychotropic drugs acting on monoamine neurotransmission are major pharmacological
treatments for neuropsychiatric conditions such as schizophrenia, depression, bipolar …

Schizophrenia is a prevalent complex trait disorder manifested by severe neurocognitive
dysfunctions and lifelong disability. During the past few years several studies have provided …

Dopamine D2 receptor antagonism is a unifying property of all antipsychotic drugs in clinical
use. Remarkably, the effector molecules through which these medications exert their actions …

The mammalian target of rapamycin (mTOR) is an ubiquitously expressed serine-threonine
kinase, which senses and integrates several intracellular and environmental cues to …

Over the last decade, finding a reliable biomarker for the early detection of schizophrenia
(Scz) has been a topic of interest. The main goal of the current review is to provide a …

Dopamine D 2 receptor antagonism is a unifying property of all antipsychotic drugs in use for
schizophrenia. While often effective at ameliorating psychosis, these drugs are largely …

Schizophrenia is a severe mental illness that afflicts nearly 1% of the world's population.
One of the cardinal pathological features of schizophrenia is perturbation in synaptic …

Serine/threonine protein kinase v-akt murine thymoma viral oncogene homolog (Akt) is one
of the survival kinases with multiple biological functions in the brain and throughout the …

Context NRG1is a schizophrenia candidate gene and plays an important role in brain
development and neural function. Schizophrenia is a complex disorder, with etiology likely …

For decades, there have been observations demonstrating significant metabolic
disturbances in people with schizophrenia including clinically relevant weight gain …