The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the
intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated …

Cell traction force plays a critical role in directing cellular functions, such as proliferation,
migration, and differentiation. Current understanding of cell traction force is largely derived …

Flow visualization technologies such as particle tracking velocimetry are broadly used for
studying three-dimensional turbulent flow in natural and industrial processes. Despite the …

Nonlinear stiffening is a ubiquitous property of major types of biopolymers that make up the
extracellular matrices (ECM) including collagen, fibrin, and basement membrane. Within the …

Collective migration of cancer cells is often interpreted using concepts derived from the
physics of active matter, but the experimental evidence is mostly restricted to observations …

The interplay between genetic transformations, biochemical communications, and physical
interactions is crucial in cancer progression. Metastasis, a leading cause of cancer-related …

Organs-on-a-chip have emerged as next-generation tissue engineered models to accurately
capture realistic human tissue behaviour, thereby addressing many of the challenges …

Successful detection and prevention of brain injuries relies on the quantitative identification
of cellular injury thresholds associated with the underlying pathology. Here, by combining a …

Cell migration and invasion play a role in many physiological and pathological processes
and are therefore subject of intensive research efforts. Despite of the intensively investigated …

Cell-extracellular matrix forces provide pivotal signals regulating diverse physiological and
pathological processes. Although mechanobiology has been widely studied in two …