Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …

The efficiency of chemotherapy in the treatment of cancer depends on the administration
schedule, such as dosage, timing and frequency, and the release control if self-assembled …

Quantitative modelling is increasingly important in cancer research, helping to integrate
myriad diverse experimental data into coherent pictures of the disease and able to …

Collective dynamics in multicellular systems such as biological organs and tissues plays a
key role in biological development, regeneration, and pathological conditions. Collective …

Invasion of malignant glioma is a highly complex phenomenon involving molecular and
cellular processes at various spatio-temporal scales, whose precise interplay is still not fully …

The mathematical modeling of tumor growth has a long history, and has been
mathematically formulated in several different ways. Here we tackle the problem in the case …

Tumor growth from a single transformed cancer cell up to a clinically apparent mass spans
many spatial and temporal orders of magnitude. Implementation of cellular automata …

In recent years cancer stem cells (CSCs) have been hypothesized to comprise only a minor
subpopulation in solid tumors that drives tumor initiation, progression, and metastasis; the so …

The ability to locally degrade the extracellular matrix (ECM) and interact with the tumor
microenvironment is a key process distinguishing cancer cells from normal cells, and is a …

Gliomas are highly invasive brain tumors that exhibit high and spatially heterogeneous cell
proliferation and motility rates. The interplay of proliferation and migration dynamics plays an …