Interventions for patent ductus arteriosus (PDA) in preterm infants: an overview of Cochrane Systematic Reviews

S Mitra, WP de Boode, DE Weisz… - Cochrane Database of …, 2023 - cochranelibrary.com
Background Patent ductus arteriosus (PDA) is associated with significant morbidity and
mortality in preterm infants. Several non‐pharmacological, pharmacological, and surgical …

Comparative safety and efficacy of paracetamol versus non‐steroidal anti‐inflammatory agents in neonates with patent ductus arteriosus: A systematic review and …

DN Katsaras, GN Katsaras… - British Journal of …, 2022 - Wiley Online Library
Aim Ibuprofen and indomethacin are the preferred drug treatment for patent ductus
arteriosus (PDA) in preterm neonates. The comparative safety and efficacy of paracetamol …

Predictors of successful patent ductus arteriosus closure with acetaminophen in preterm infants

R Vaidya, A Knee, Y Paris, R Singh - Journal of Perinatology, 2021 - nature.com
Objective Evaluate predictors of successful PDA closure following acetaminophen treatment.
Study design Retrospective cohort study of≤ 30 weeks GA infants born from 1 January 2013 …

Low dose paracetamol for management of patent ductus arteriosus in very preterm infants: a randomised non-inferiority trial

H Balasubramanian, V Jain, P Bhalgat… - Archives of Disease in …, 2023 - fn.bmj.com
Objective To compare the efficacy of low dose-short course intravenous paracetamol with a
conventional dose regimen for early targeted closure of patent ductus arteriosus (PDA) …

Comparison of various pharmacologic agents in the management of hemodynamically significant patent ductus arteriosus in preterm: a network meta-analysis and risk …

S Eursiriwan, C Okascharoen, SAO Vallibhakara… - Biomedicine …, 2022 - karger.com
Introduction: Various pharmacological treatments are available for preterm infants with
patent ductus arteriosus (PDA), but their risks and benefits are controversial. This study …

Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants

B Jasani, S Mitra, PS Shah - Cochrane Database of Systematic …, 2022 - cochranelibrary.com
Background The different management strategies for patent ductus arteriosus (PDA) in
preterm infants are expectant management, surgery, or medical treatment with non‐selective …

Paracetamol vs. ibuprofen in preterm infants with hemodynamically significant patent ductus arteriosus: a non-inferiority randomized clinical trial protocol

A García-Robles, A Gimeno Navarro… - Frontiers in …, 2020 - frontiersin.org
Background: Currently, the first line treatment of persistent ductus arteriosus (PDA) is either
indomethacin or ibuprofen. However, the potentially life-threatening side effects associated …

A network meta-analysis of intravenous versus oral acetaminophen for patent ductus arteriosus

A Olowoyeye, O Nnamdi-Nwosu, M Manalastas… - Pediatric …, 2023 - Springer
The use of acetaminophen to close a PDA in preterm infants is increasing; however, the
most effective route of administration is not yet known. This network meta-analysis compares …

[HTML][HTML] Cost-effectiveness analysis of ibuprofen versus indomethacin or paracetamol for the treatment of patent ductus arteriosus in preterm neonates

S Al-Shaibi, D Abushanab, F Abounahia… - Current Problems in …, 2023 - Elsevier
This was a first-time evaluation that sought to analyze the cost-effectiveness of oral
paracetamol and intravenous (IV) indomethacin as alternatives to ibuprofen for PDA in …

Response of the ductus arteriosus to acetaminophen or indomethacin in extremely low birth weight infants

CC Sutton, JC Slaughter, MW Alrifai, J Hale… - Journal of …, 2024 - nature.com
Objective Acetaminophen and indomethacin are used for medical management of a patent
ductus arteriosus. This study compared the efficacy of these agents in ELBW infants. Study …