Neuroinflammation is a key pathologic hallmark of numerous neurologic diseases, however,
its exact role in vivo is yet to be fully understood. PET imaging enables investigation …

Following the impressive progress in the treatment of relapsing–remitting multiple sclerosis
(MS), the major challenge ahead is the development of treatments to prevent or delay the …

Immunotherapy is innovating clinical cancer management. Nevertheless, only a small
fraction of patient's benefit from current immunotherapies. To improve clinical management …

Radiological imaging is an integral component of cancer care, including diagnosis, staging,
and treatment response monitoring. It contains rich information about tumor phenotypes that …

The recent clinical success of cancer immunotherapy has renewed interest in the
development of tools to image the immune system. In general, immunotherapies attempt to …

In situ cancer vaccines are under active clinical investigation, given their reported ability to
eradicate both local and disseminated malignancies. Intratumoral vaccine administration is …

With further research into the molecular mechanisms and roles linking immune suppression
and restraint of (pre) malignancies, immunotherapies have revolutionized clinical strategies …

Brown and brown-like adipose tissues have attracted significant attention for their role in
metabolism and therapeutic potential in diabetes and obesity. Despite compelling evidence …

Dramatic, but uneven, progress in the development of immunotherapies for cancer has
created a need for better diagnostic technologies including innovative non-invasive imaging …

Abstract Purpose of Review Multiple sclerosis is characterized by a diverse and complex
pathology. Clinical relapses, the hallmark of the disease, are accompanied by focal white …