Purpose Numerous studies have shown that the risk of fracture is increased by long-term
antiepileptic drugs (AEDs). Valproic acid (VPA) is one of the most commonly used AEDs. In …

Purpose The effects of levetiracetam (LEV) on bone mineral density (BMD) and bone
metabolism are currently inconclusive, and this study was designed to answer this question …

Background Previous studies have reported that long-term use of valproic acid can cause
changes in bone metabolism in children. We conducted this meta-analysis to determine the …

Epilepsy is considered a major serious chronic neurological disorder, characterized by
recurrent seizures. It is usually associated with a history of a lesion in the nervous system …

Abstract Purpose of Review Psychotropics are prescribed to youth at rapidly growing rates
and may negatively impact bone health. Little awareness exists of this association among …

Purpose: The effects of antiseizure medications (ASMs) on bone metabolism is inconsistent.
Most studies are in high income settings and none from sub-Saharan Africa. Methods: A …

Abstract Aim Vitamin D (Vit D) has been considered as a neurosteroid and has a pivotal role
in neuroprotection including epilepsy. Vit D regulator acts via a Vit D receptor (VDR) …

Objetivo: explorar la asociación entre la baja densidad mineral ósea (DMO) e indicadores
bioquímicos y hormonales del metabolismo óseo en niños con PC cuadripléjica. Métodos …

Purpose Our aim was to investigate any adverse effects of long-term polytherapy (VPA and
add-on-therapy) on bone biochemical markers in ambulatory children and adolescents with …

Materials and Methods: In this cross-sectional observational study conducted at the
Department of Neurology Government Medical College, Kota, 135 epilepsy patients who …