Structural biology of cilia and intraflagellar transport

N Klena, G Pigino - Annual review of cell and developmental …, 2022 - annualreviews.org
Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …

The intraflagellar transport machinery

M Taschner, E Lorentzen - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Eukaryotic cilia and flagella are evolutionarily conserved organelles that protrude from the
cell surface. The unique location and properties of cilia allow them to function in vital …

WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data

AD Holdorf, DP Higgins, AC Hart, PR Boag… - Genetics, 2020 - academic.oup.com
The emergence of large gene expression datasets has revealed the need for improved tools
to identify enriched gene categories and visualize enrichment patterns. While gene …

[HTML][HTML] Evolution: Tracing the origins of centrioles, cilia, and flagella

Z Carvalho-Santos, J Azimzadeh… - The Journal of cell …, 2011 - ncbi.nlm.nih.gov
Centrioles/basal bodies (CBBs) are microtubule-based cylindrical organelles that nucleate
the formation of centrosomes, cilia, and flagella. CBBs, cilia, and flagella are ancestral …

C. elegans dauer formation and the molecular basis of plasticity

N Fielenbach, A Antebi - Genes & development, 2008 - genesdev.cshlp.org
Because life is often unpredictable, dynamic, and complex, all animals have evolved
remarkable abilities to cope with changes in their external environment and internal …

Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Motility and more: the flagellum of Trypanosoma brucei

G Langousis, KL Hill - Nature Reviews Microbiology, 2014 - nature.com
Trypanosoma brucei is a pathogenic unicellular eukaryote that infects humans and other
mammals in sub-Saharan Africa. A central feature of trypanosome biology is the single …

Cilia in the CNS: the quiet organelle claims center stage

A Louvi, EA Grove - Neuron, 2011 - cell.com
The primary cilium is a cellular organelle that is almost ubiquitous in eukaryotes, yet its
functions in vertebrates have been slow to emerge. The last fifteen years have been marked …

Architecture and function of IFT complex proteins in ciliogenesis

M Taschner, S Bhogaraju, E Lorentzen - Differentiation, 2012 - Elsevier
Cilia and flagella (interchangeable terms) are evolutionarily conserved organelles found on
many different types of eukaryotic cells where they fulfill important functions in motility …

A high-resolution morphological and ultrastructural map of anterior sensory cilia and glia in Caenorhabditis elegans

DB Doroquez, C Berciu, JR Anderson, P Sengupta… - Elife, 2014 - elifesciences.org
Many primary sensory cilia exhibit unique architectures that are critical for transduction of
specific sensory stimuli. Although basic ciliogenic mechanisms are well described, how …