Abstract Purpose of Review The metabolic syndrome is a pathological state in which one of
the key components is insulin resistance. A wide spectrum of body compartments is involved …

The concerning worldwide increase of obesity and chronic metabolic diseases, such as
T2D, dyslipidemia, and cardiovascular disease, motivates further investigations into …

Childhood obesity is a serious public health crisis and a critical factor that determines future
obesity prevalence. Signals affecting adipocyte development in early postnatal life have a …

The present study sought to identify gene networks that are hallmarks of the developing
inguinal subcutaneous adipose tissue (iWAT) and the interscapular brown adipose tissue …

Background: Peripheral alterations of mitochondrial DNA copy number (mtDNAcn) in obesity
and associated co-morbidities have been previously shown. Furthermore, the possibility that …

The genome of human adipose-derived stem cells (ADSCs) from abdominal and
gluteofemoral adipose tissue depots are maintained in depot-specific stable epigenetic …

Brown adipose tissue (BAT) generates heat through non-shivering thermogenesis, and
increasing BAT amounts or activity could facilitate obesity treatment and provide metabolic …

The marker genes associated with white adipocytes and brown adipocytes have been
previously identified; however, these markers have not been updated in several years, and …

The Tabula Sapiens is a reference human cell atlas containing single cell transcriptomic
data from more than two dozen organs and tissues. Here we report Tabula Sapiens 2.0 …

The written thesis describes thermogenic adipocytes in the inguinal adipose tissue of infant
mice. A mitochondria to nucleus signaling was discovered which supports beige …