Susceptibility of Mycobacterium abscessus to antimycobacterial drugs in preclinical models

A Obregón-Henao, KA Arnett… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Over the last 10 years, Mycobacterium abscessus group strains have emerged as important
human pathogens, which are associated with significantly higher fatality rates than any other …

Subunit vaccine protects against a clinical isolate of Mycobacterium avium in wild type and immunocompromised mouse models

SE Larsen, VA Reese, T Pecor, BJ Berube… - Scientific reports, 2021 - nature.com
The nontuberculous mycobacteria (NTM) Mycobacterium avium is a clinically significant
pathogen that can cause a wide range of maladies, including tuberculosis-like pulmonary …

[HTML][HTML] Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection

M Steigedal, A Marstad, M Haug, JK Damås… - The Journal of …, 2014 - journals.aai.org
Competition for iron is a critical component of successful bacterial infections, but the
underlying in vivo mechanisms are poorly understood. We have previously demonstrated …

The protective effects of oral low-dose quercetin on diabetic nephropathy in hypercholesterolemic mice

IBS Gomes, ML Porto, MC Santos… - Frontiers in …, 2015 - frontiersin.org
Aims: Diabetic nephropathy (DN) is one of the most important causes of chronic renal
disease, and the incidence of DN is increasing worldwide. Considering our previous report …

[HTML][HTML] Immunogenicity and protection against mycobacterium avium with a heterologous RNA prime and protein boost vaccine regimen

M Rais, H Abdelaal, VA Reese, D Ferede, SE Larsen… - Tuberculosis, 2023 - Elsevier
Prophylactic efficacy of two different delivery platforms for vaccination against
Mycobacterium avium (M. avium) were tested in this study; a subunit and an RNA-based …

Global Assessment of Mycobacterium avium subsp. hominissuis Genetic Requirement for Growth and Virulence

MS Dragset, TR Ioerger, M Loevenich, M Haug… - Msystems, 2019 - Am Soc Microbiol
Nontuberculous mycobacterial infections caused by the opportunistic pathogen
Mycobacterium avium subsp. hominissuis (MAH) are currently receiving renewed attention …

Photochemical internalization of peptide antigens provides a novel strategy to realize therapeutic cancer vaccination

M Haug, G Brede, M Håkerud, AG Nedberg… - Frontiers in …, 2018 - frontiersin.org
Effective priming and activation of tumor-specific CD8+ cytotoxic T lymphocytes (CTLs) is
crucial for realizing the potential of therapeutic cancer vaccination. This requires cytosolic …

Mycobacterium avium Infection in a C3HeB/FeJ Mouse Model

D Verma, M Stapleton, J Gadwa… - Frontiers in …, 2019 - frontiersin.org
Infections caused by Mycobacterium avium complex (MAC) species are increasing
worldwide, resulting in a serious public health problem. Patients with MAC lung disease face …

Metformin improves Mycobacterium avium infection by strengthening macrophage antimicrobial functions

SD Mediaas, M Haug, C Louet, SGF Wahl… - Frontiers in …, 2024 - frontiersin.org
Introduction The incidence and prevalence of infections with non-tuberculous mycobacteria
such as Mycobacterium avium (Mav) are increasing. Prolonged drug regimens, inherent …

Early IL-17A production helps establish Mycobacterium intracellulare infection in mice

BG Jung, B Samten, K Dean, RJ Wallace Jr… - PLoS …, 2022 - journals.plos.org
Nontuberculous mycobacteria (NTM) infection is common in patients with structural lung
damage. To address how NTM infection is established and causes lung damage, we …