Conspectus Aerobic organisms have evolved to activate oxygen from the atmosphere, which
allows them to catalyze the oxidation of different kinds of substrates. This activation of …

This review describes the historical difficulties in devising a kinetically satisfactory
mechanism for the classical catalase after its identification as a unique catalytic entity in …

Catalases are ubiquitous enzymes that prevent cell oxidative damage by degrading
hydrogen peroxide to water and oxygen (2H2O2→ 2 H2O+ O2) with high efficiency. The …

Catalases are ubiquitous enzymes that prevent cell oxidative damage by degrading
hydrogen peroxide to water and oxygen (2H2O2→ 2H2O+ O2) with high efficiency. The …

Ni-containing carbon monoxide dehydrogenases (CODH), present in many anaerobic
microorganisms, catalyze the reversible oxidation of CO to CO2 at the so-called C-cluster …

Oxygen activation in all heme enzymes requires the formation of high oxidation states of
iron, usually referred to as ferryl heme. There are two known intermediates: Compound I and …

Abstract l-Tryptophan is an essential amino acid for mammals. It is utilized not only for
protein synthesis but also for the biosynthesis of serotonin and melatonin by the serotonin …

Catalase, a heme enzyme, which catalyzes decomposition of hydrogen peroxide to water
and molecular oxygen, is one of the main enzymes of the antioxidant defense system of the …

The mechanisms of oxidative N-dealkylation of amines by heme enzymes including
peroxidases and cytochromes P450 and by functional models for the active Compound I …

Catalases and peroxidases are ubiquitous heme enzymes that catalyze the removal of
hydrogen peroxide (H2O2). Both enzymes use one molecule of hydrogen peroxide to form a …