Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

Abstract α-Glucosidase enzyme inhibition is an effective therapeutic decorum in the
treatment of type 2 diabetes mellitus. Since 1990, three α-glucosidase inhibitors are known …

In the present study, 1-Benzyl-4-(N-Boc-amino) piperidine was characterized by
spectroscopic investigations employing FT-IR, FT-Raman, UV-Vis and NMR (13 C, 1 H) …

Building blocks are the molecular foundations for drug molecule design. The building block
is one of the determining factors of final compound qualities in any given medicinal …

Diarylprolinol silyl ethers are among the most utilized stereoselective organocatalysts for the
construction of complex molecules. With their debut in 2005, these catalysts have been …

Abstract According to the World Health Organization (WHO), depression is a common
mental disorder and includes complex interaction between social and psychological …

Covalent protein kinase inhibitors exploit currently noncatalytic cysteines in the adenosine
5′-triphosphate (ATP)-binding site via electrophiles directly appended to a reversible …

Earth-abundant metal (EAM) catalysis can have profound impact in the pharmaceutical
industry in terms of sustainability and cost improvements from replacing precious metals like …

Reaction rate acceleration using green methods is an intriguing area of research for
chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of …

Alkaloids are nitrogen-containing natural products found in bacteria, fungi, animals, and
plants with complex and diverse structures. The widespread distribution of alkaloids along …