This review presents the most elegant and promising set of synthetic routes for the synthesis
of 2‐aminothiophenes by the Gewald reaction. This reaction has applications in several …

The relevance of Retinoic acid receptor-related orphan receptors in cancer progression has
sparked interest in developing multifunctional therapeutics. In the search for potentially …

Background: Considering the need for the development of new antitumor drugs, associated
with the great antitumor potential of thiophene and thiosemicarbazonic derivatives, in this …

Three Schiff bases were synthesized from 3, 3-methylenedianiline and used as corrosion
inhibitors for 1018 carbon steel in 0.5 M sulfuric acid. New compounds include 3 …

Background: Multicomponent reactions are highly useful in synthesizing natural products
and bioactive molecules. Out of several MCRs, although utilized widely, some remain …

Aim: In order to identify and evaluate the metal-derived synthetic antioxidants having high
free radicals scavenging capacity related to various disorders has received much interest in …

In spite of great progress in understanding cancer biology, current therapeutic procedures
remain unsatisfactory. Chemotherapy is often followed by secondary effects with cellular …

Mixed ligand complexes included Schiff base derivative ligand (L1) have been produced by
condensed {3-amino-1-phenyl-2-pyrazolin-5-one (APO)} with o-phathalaldehyde and …

Amino-6-oxo-4, 5, 6, 7-tetrahydrobenzo [b] thiophene-3-carbonitrile (3) was prepared from
the reaction of cyclohexane-1, 4-dione with elemental sulfur and malononitrile in 1, 4 …

The present work details the synthesis of several intriguing nitrogenous heterocycles
utilizing a cyano-N-aryl-acetamide-reagent, notably chlorinated thiazolidine, thiophene and …