Adipose tissue remodeling in pathophysiology

C Auger, S Kajimura - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Rather than serving as a mere onlooker, adipose tissue is a complex endocrine organ and
active participant in disease initiation and progression. Disruptions of biological processes …

White adipose tissue browning in critical illness: a review of the evidence, mechanisms and future perspectives

E Alipoor, MJ Hosseinzadeh‐Attar, M Rezaei… - Obesity …, 2020 - Wiley Online Library
Observational studies suggest better clinical outcomes following critical illness in patients
with overweight and obesity (obesity paradox). An understanding of the morphologic …

The surviving sepsis campaign: basic/translational science research priorities

CS Deutschman, J Hellman, RF Roca… - Intensive care medicine …, 2020 - Springer
Objectives Expound upon priorities for basic/translational science identified in a recent
paper by a group of experts assigned by the Society of Critical Care Medicine and the …

The gut microbiota metabolite succinate promotes adipose tissue browning in Crohn's disease

D Monfort-Ferré, A Caro, M Menacho… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Crohn's disease [CD] is associated with complex microbe–
host interactions, involving changes in microbial communities, and gut barrier defects …

[HTML][HTML] Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice

M Li, M Barros-Pinkelnig, G Weiss, PCN Rensen… - Journal of Lipid …, 2024 - Elsevier
Brown adipose tissue (BAT) combusts lipids and glucose to generate heat. Via this process
of nonshivering thermogenesis, BAT plays a pivotal role in thermoregulation in cold …

Supplementation of fermented barley extracts with lactobacillus plantarum dy-1 inhibits obesity via a UCP1-dependent mechanism

X Xiang, BAI Juan, MS Li, JY Zhang, XJ Sun… - Biomedical and …, 2019 - Elsevier
Objective We aimed to explore how fermented barley extracts with Lactobacillus plantarum
dy-1 (LFBE) affected the browning in adipocytes and obese rats. Methods In vitro, 3T3-L1 …

Browning of white adipose tissue may be an appropriate adaptive response to critical illness

SA McClave, RG Martindale - Journal of Parenteral and Enteral …, 2024 - Wiley Online Library
Both the baseline amount of brown adipose tissue (BAT) and the capacity to stimulate
browning of white adipose tissue (WAT) may provide a protective effect to the patient in a …

[HTML][HTML] A Closer Look into White Adipose Tissue Biology and the Molecular Regulation of Stem Cell Commitment and Differentiation

PD Dowker-Key, PK Jadi, NB Gill, KN Hubbard… - Genes, 2024 - mdpi.com
White adipose tissue (WAT) makes up about 20–25% of total body mass in healthy
individuals and is crucial for regulating various metabolic processes, including energy …

High-fat diet increases mortality and intensifies immunometabolic changes in septic mice

SV Gomes, BV Dias, PAM Júnior, RR Pereira… - The Journal of …, 2023 - Elsevier
Immunometabolic changes in the liver and white adipose tissue caused by high-fat (HF) diet
intake may worse metabolic adaptation and protection against pathogens in sepsis. We …

Antimicrobial and Immunomodulatory Effects of Selected Chemokine and Antimicrobial Peptide on Cytokine Profile during Salmonella Typhimurium Infection in …

A Tuxpan-Pérez, MA Ibarra-Valencia, BE Estrada… - Antibiotics, 2022 - mdpi.com
The antimicrobial and immunomodulatory capacities of the peptide Css54 and the
chemokine MCP-1 were tested. The first, a peptide isolated from the venom of the scorpion …