Global aspects of viral glycosylation
I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …
infections of different severity, ranging from no or very few symptoms to lethal disease as …
Hepatitis C virus vaccine: challenges and prospects
The hepatitis C virus (HCV) causes both acute and chronic infection and continues to be a
global problem despite advances in antiviral therapeutics. Current treatments fail to prevent …
global problem despite advances in antiviral therapeutics. Current treatments fail to prevent …
[PDF][PDF] Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: the multiethnic cohort
Chronic liver disease (CLD) and cirrhosis are major sources of morbidity and mortality in the
United States. Little is known about the epidemiology of these two diseases in ethnic …
United States. Little is known about the epidemiology of these two diseases in ethnic …
Influence of glycosylation on the immunogenicity and antigenicity of viral immunogens
A key aspect of successful viral vaccine design is the elicitation of neutralizing antibodies
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …
targeting viral attachment and fusion glycoproteins that embellish viral particles. This …
Human lectins and their roles in viral infections
CP Mason, AW Tarr - Molecules, 2015 - mdpi.com
Innate recognition of virus proteins is an important component of the immune response to
viral pathogens. A component of this immune recognition is the family of lectins; pattern …
viral pathogens. A component of this immune recognition is the family of lectins; pattern …
Mannose binding lectin gene 2 (rs1800450) missense variant may contribute to development and severity of COVID-19 infection
Background/objectives COVID-19 followed a mortal course in some young patients without
any underlying factors, however, it followed a very benign course in some very older …
any underlying factors, however, it followed a very benign course in some very older …
Secreted NS1 protects dengue virus from mannose-binding lectin–mediated neutralization
S Thiemmeca, C Tamdet, N Punyadee… - The Journal of …, 2016 - journals.aai.org
Abstract Flavivirus nonstructural protein 1 (NS1) is a unique secreted nonstructural
glycoprotein. Although it is absent from the flavivirus virion, intracellular and extracellular …
glycoprotein. Although it is absent from the flavivirus virion, intracellular and extracellular …
Collectins: innate immune pattern recognition molecules
Collectins are collagen-containing C-type (calcium-dependent) lectins which are important
pathogen pattern recognising innate immune molecules. Their primary structure is …
pathogen pattern recognising innate immune molecules. Their primary structure is …
AB cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses
Endogenous retroviruses (ERVs), comprising a substantial portion of the vertebrate genome,
are remnants of ancient genetic invaders. ERVs with near-intact coding potential reactivate …
are remnants of ancient genetic invaders. ERVs with near-intact coding potential reactivate …
MBL-associated serine proteases (MASPs) and infectious diseases
The lectin pathway of the complement system has a pivotal role in the defense against
infectious organisms. After binding of mannan-binding lectin (MBL), ficolins or collectin 11 to …
infectious organisms. After binding of mannan-binding lectin (MBL), ficolins or collectin 11 to …