Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy
medicine and medicine be thy food.” Exploring the association between diet and health …

NF-κB, a transcription factor first discovered in 1986, is now known to be closely connected
to the process of tumorogenesis based on a multiplicity of evidence.(1) NF-κB is activated in …

Sesquiterpene lactones are a large group of secondary plant metabolites mostly known from
the Asteraceae family. They exert a broad variety of different biological activities. This review …

Sesquiterpene lactones are of considerable interest due to their potent bioactivities,
including cancer cell cytotoxicity and antineoplastic efficacy in in vivo studies. Among these …

Sesquiterpene lactones (SLs) constitute a large and diverse group of biologically active
plant compounds that possess anti-inflammatory and antitumor activity. The subclass …

Cancer is one of the most dangerous diseases that are rapidly increasing globally. After
heart disease, it is the second leading cause of death, accounting for seven million deaths …

Human nuclear receptors (NRs) are a family of forty-eight transcription factors that modulate
gene expression both spatially and temporally. Numerous biochemical, physiological, and …

This book presents up-to-date information on a total of 75 native and non-native medicinal
plants growing in Singapore. Comprehensive and useful information from the published …

Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to
exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells …

Bone loss or osteoporosis, is a slow-progressing disease that results from dysregulation of
pro-inflammatory cytokines. The FDA has approved number of drugs for bone loss …