Hypertriglyceridemia in Apoa5–/– mice results from reduced amounts of lipoprotein lipase in the capillary lumen
Y Yang, AP Beigneux, W Song, H Jung… - The Journal of …, 2023 - Am Soc Clin Investig
Why apolipoprotein AV (APOA5) deficiency causes hypertriglyceridemia has remained
unclear, but we have suspected that the underlying cause is reduced amounts of lipoprotein …
unclear, but we have suspected that the underlying cause is reduced amounts of lipoprotein …
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing
W Song, AP Beigneux, TA Weston… - Proceedings of the …, 2023 - National Acad Sciences
Lipoprotein lipase (LPL), the enzyme that carries out the lipolytic processing of triglyceride-
rich lipoproteins (TRLs), is synthesized by adipocytes and myocytes and secreted into the …
rich lipoproteins (TRLs), is synthesized by adipocytes and myocytes and secreted into the …
[HTML][HTML] APOA5 Deficiency Causes Hypertriglyceridemia by Reducing Amounts of Lipoprotein Lipase in Capillaries
Apolipoprotein AV (APOA5) deficiency causes hypertriglyceridemia in mice and humans.
For years, the cause remained a mystery, but the mechanisms have now come into focus …
For years, the cause remained a mystery, but the mechanisms have now come into focus …
Hyperlipidaemia treatment and gut microbiology
L Zhe, Y ChunLi - Frontiers in Microbiology, 2025 - frontiersin.org
Numerous studies have shown that hyperlipidaemia is closely related to the gut microbiota,
and the study of microbiota in the treatment of hyperlipidaemia is undoubtedly a new target …
and the study of microbiota in the treatment of hyperlipidaemia is undoubtedly a new target …
[HTML][HTML] Distinct strategies for intravascular triglyceride metabolism in hearts of mammals and lower vertebrate species
W Song, Y Yang, AP Tran, TA Weston, H Jung… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Lipoprotein lipase (LPL) and multiple regulators of LPL activity (eg, APOC2 and ANGPTL4)
are present in all vertebrates, but GPIHBP1—the endothelial cell (EC) protein that captures …
are present in all vertebrates, but GPIHBP1—the endothelial cell (EC) protein that captures …
Effects of myonectin on porcine intramuscular adipocyte differentiation and exogenous free fatty acid utilization
Z Sun, Z Liu, J Xi, Y Liu, Z Zheng, N Li, Z Li… - Animal …, 2023 - Taylor & Francis
As an important factor secreted by skeletal muscle, myonectin can regulate lipid metabolism
and energy metabolism, but its role in the utilization of peripheral free fatty acids (FFAs) by …
and energy metabolism, but its role in the utilization of peripheral free fatty acids (FFAs) by …
ANGPTL4—A protein involved in glucose metabolism, lipid metabolism, and tumor development
Z Xu, G Jiang - The Journal of Gene Medicine, 2024 - Wiley Online Library
Since ANGPTL4 was discovered to be involved in lipid metabolism in 2000 for the first time,
Angptl4 has attracted the attention of researchers. With the further research, it was found that …
Angptl4 has attracted the attention of researchers. With the further research, it was found that …
Lipoprotein Lipase Activity Does Not Differ in the Serum Environment of Vegans and Omnivores
Although vegan diets have been reported to be associated with a reduced risk of
cardiovascular disease, it was not known whether this might be partly due to vegan diets' …
cardiovascular disease, it was not known whether this might be partly due to vegan diets' …