Abstract T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ,
and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense …

In recent years the number of reports describing phenotypically and functionally distinct
subsets of human blood leukocytes, and in particular of subtypes of antigen-presenting cells …

The relevance of cyclooxygenases (COX)-1 and-2 and their products to inflammation,
thrombosis and gastroprotection are well known. Their importance in the immune response …

Background: In several neoplastic diseases, including breast cancer, immunosuppression
correlates with disease stage, progression, and outcome. Thus, thorough analysis of …

Despite the availability of effective treatment for several decades, leprosy remains an
important medical problem in many regions of the world. Infection with Mycobacterium …

Lipid droplets induced by Mycobacterium leprae in macrophages are Toll-like receptor-
regulated organelles involved in eicosanoid formation and leprosy pathogenesis. A hallmark …

Single-nucleotide polymorphisms within the genes coding for tumor necrosis factor (TNF)–α
and interleukin (IL)–10 have been associated with several infectious diseases. To determine …

The past few years have been very productive concerning the identification of genes
associated with leprosy. Candidate gene strategies using both case–control and family …

A hanseníase, cujo agente etiológico Mycobacterium Ieprae, é doença de amplo espectro
clínico e imunopatológico. Suas apresentações clínicas estão correlacionadas com padrões …

Leprosy, also known as Hansen's disease, is a chronic infectious disease caused by
Mycobacterium leprae in which susceptibility to the mycobacteria and its clinical …