How radiation kills cells: Survival of Deinococcus radiodurans and Shewanella oneidensis under oxidative stress

D Ghosal, MV Omelchenko… - FEMS microbiology …, 2005 - academic.oup.com
We have recently shown that Deinococcus radiodurans and other radiation resistant
bacteria accumulate exceptionally high intracellular manganese and low iron levels. In …

Why is Deinococcus radiodurans so resistant to ionizing radiation?

JR Battista, AM Earl, MJ Park - Trends in microbiology, 1999 - cell.com
When exponential-phase cultures of Deinococcus radiodurans are exposed to a 5000-Gray
dose of γ radiation, individual cells suffer massive DNA damage. Despite this insult to their …

Antioxidant properties of probiotics and their protective effects in the pathogenesis of radiation-induced enteritis and colitis

BG Spyropoulos, EP Misiakos, C Fotiadis… - Digestive diseases and …, 2011 - Springer
Radiation therapy has become one of the most important treatment modalities for human
malignancy, but certain immediate and delayed side-effects on the normal surrounding …

[HTML][HTML] Efficiency of thyme and oregano essential oils in counteracting the hazardous effects of malathion in rats

FA Al-Saeed, SS Abd-Elghfar, ME Ali - Animals, 2024 - mdpi.com
Simple Summary Malathion (MLT) is one of the most widely used pesticides and may pose
multiple hazards to humans and animals. Some therapeutic herbs have the potential to …

[HTML][HTML] Whole brain radiation-induced cognitive impairment: pathophysiological mechanisms and therapeutic targets

YW Lee, HJ Cho, WH Lee… - Biomolecules & …, 2012 - ncbi.nlm.nih.gov
Radiation therapy, the most commonly used for the treatment of brain tumors, has been
shown to be of major significance in tu-mor control and survival rate of brain tumor patients …

Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis

SA Reisman, CYI Lee, CJ Meyer… - Radiation …, 2014 - meridian.allenpress.com
Free radicals produced during cancer radiotherapy often leads to dermatitis, with the insult
ranging from mild erythema to moist desquamation and ulceration. This toxicity can be dose …

Chemical and biological basis for development of novel radioprotective drugs for cancer therapy

R Checker, RS Patwardhan, S Jayakumar… - Free Radical …, 2021 - Taylor & Francis
Ionizing radiation (IR) causes chemical changes in biological systems through direct
interaction with the macromolecules or by causing radiolysis of water. This property of IR is …

[HTML][HTML] Magnesium isoglycyrrhizinate ameliorates radiation-induced pulmonary fibrosis by inhibiting fibroblast differentiation via the p38MAPK/Akt/Nox4 pathway

Q Yang, P Zhang, T Liu, X Zhang, X Pan, Y Cen… - Biomedicine & …, 2019 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF) is a severe complication in patients treated
with thoracic irradiation. Until now, there are no effective therapeutic drugs for RIPF. In the …

Mitigation of radiation-induced lung injury by genistein and EUK-207

J Mahmood, S Jelveh, V Calveley, A Zaidi… - … journal of radiation …, 2011 - Taylor & Francis
Purpose: We examined the effects of genistein and/or Eukarion (EUK)-207 on radiation-
induced lung damage and investigated whether treatment for 0–14 weeks (wks) post …

Possible role of vitamin E, coenzyme Q10 and rutin in protection against cerebral ischemia/reperfusion injury in irradiated rats

AA Abd-El-Fattah, MM El-Sawalhi… - … journal of radiation …, 2010 - Taylor & Francis
Purpose: To investigate the possible role of vitamin E, coenzyme Q10 and rutin in
ameliorating the biochemical changes in brain and serum induced by cerebral …