[PDF][PDF] Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …
decades. During childhood and adolescence, cortical development progresses from lower …
[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …
Standardizing workflows in imaging transcriptomics with the abagen toolbox
Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes
Patients with major depressive disorder (MDD) exhibit concurrent deficits in both sensory
and higher-order cognitive processing. Connectome studies have suggested a principal …
and higher-order cognitive processing. Connectome studies have suggested a principal …
Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: a Mendelian randomization study
Importance Previous in vitro and postmortem research suggests that inflammation may lead
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …
Individual-specific areal-level parcellations improve functional connectivity prediction of behavior
Resting-state functional magnetic resonance imaging (rs-fMRI) allows estimation of
individual-specific cortical parcellations. We have previously developed a multi-session …
individual-specific cortical parcellations. We have previously developed a multi-session …
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …
arise from molecular perturbations or connectome miswiring. The unique and shared …
Sensory-motor cortices shape functional connectivity dynamics in the human brain
Large-scale biophysical circuit models provide mechanistic insights into the micro-scale and
macro-scale properties of brain organization that shape complex patterns of spontaneous …
macro-scale properties of brain organization that shape complex patterns of spontaneous …
Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder
AJ Cutler, GW Mattingly, V Maletic - Translational Psychiatry, 2023 - nature.com
The pathophysiology of major depressive disorder (MDD) is thought to result from impaired
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …