Role of inflammation and oxidative stress in chemotherapy-induced neurotoxicity

P Gupta, TK Makkar, L Goel, M Pahuja - Immunologic Research, 2022 - Springer
Chemotherapeutic agents may adversely affect the nervous system, including the neural
precursor cells as well as the white matter. Although the mechanisms are not completely …

Modulation of cellular redox parameters for improving therapeutic responses in multiple myeloma

A Allegra, C Petrarca, M Di Gioacchino, M Casciaro… - Antioxidants, 2022 - mdpi.com
Raised oxidative stress and abnormal redox status are typical features of multiple myeloma
cells, and the identification of the intimate mechanisms that regulate the relationships …

Targeting reactive oxygen species metabolism to induce myeloma cell death

M Caillot, H Dakik, F Mazurier, B Sola - Cancers, 2021 - mdpi.com
Simple Summary Multiple myeloma (MM) is a neoplastic disease of plasma cells,
characterized by a complex array of clinical manifestations. Despite extensive efforts and …

Immunomodulators in newly diagnosed multiple myeloma: current and future concepts

M Delforge, S Vlayen, N Kint - Expert Review of Hematology, 2021 - Taylor & Francis
Introduction: Impressive therapeutic progress is being made in the management of multiple
myeloma (MM). his progress is related to the introduction of several new classes of …

Ubiquitination of proteins involved in metabolism and immunomodulatory drug sensitivity in lymphocytes

R Harris - 2022 - repository.cam.ac.uk
Proteins undergo post-translational modifications, such as ubiquitination and
phosphorylation, which can alter their activity, localisation and stability, making a cell …

[PDF][PDF] Oxidative Stress in Multiple Myeloma Pathophysiology and Treatment

T Achladas, K Lafara, K Tsioni, K Kyrka, G Koktsidis… - 2024 - researchgate.net
Multiple myeloma (MM) is a clonal plasma cell proliferation disease characterized by an
abnormal monoclonal protein, leading to specific-organ damage. Nowadays, significant …

The role of cereblon in lenalidomide therapy of del (5q) myelodysplastic syndrome

R Bokorová - 2022 - dspace.cuni.cz
Myelodysplastic syndrome (MDS) with deletion of the long arm of the chromosome 5 (5q-
syndrome, del (5q)) can be characterized by anemia, macrocytosis, a normal or high platelet …

Funktionelle Analyse von patientenspezifischen Mutationen in IKZF1/3 als mögliche Resistenzmechanismen in der Therapie des refraktären und rezidivierten …

T Demler - 2021 - opus.bibliothek.uni-wuerzburg.de
Trotz einer Vielzahl neuer Therapieansätze in den letzten Jahren, die ein längeres
Überleben der Patienten ermöglichen, stellt das multiple Myelom weiterhin eine unheilbare …

[引用][C] Funktionelle Analyse von patientenspezifischen Mutationen in IKZF1/3 als mögliche Resistenzmechanismen in der Therapie des refraktären und rezidivierten …

T Demler

[引用][C] Curriculum Vitae and Bibliography

R Fonseca - Science, 2002