Perioperative stroke is a potentially devastating complication in patients undergoing
noncardiac, nonneurological surgery. This scientific statement summarizes established risk …

Background The optimal haemoglobin threshold for use of red blood cell (RBC) transfusions
in anaemic patients remains an active field of research. Blood is a scarce resource, and in …

While patient blood management (PBM) initiatives are increasingly adopted across the
globe as part of standard of care, there is need for a clear and widely accepted definition of …

Importance Blood transfusion is one of the most frequently used therapies worldwide and is
associated with benefits, risks, and costs. Objective To develop a set of evidence-based …

Background We reported previously that, in patients undergoing cardiac surgery who were
at moderate-to-high risk for death, a restrictive transfusion strategy was noninferior to a …

Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …

Stored red blood cells (RBCs) incur biochemical and morphological changes, collectively
termed the storage lesion. Functionally, the storage lesion manifests as slower oxygen …

Cardiorenal syndrome includes a spectrum of disorders of the kidneys and heart in which
loss of function in one organ contributes to reduced function in the other organ. Cardiorenal …

Optimal red cell transfusion support in myelodysplastic syndromes (MDS) has not been
tested and established. The aim of this study was to demonstrate feasibility of recruitment …

Objective Anemia is very common in critical care patients, on admission (affecting about two-
thirds of patients), but also during and after their stay, due to repeated blood loss, the effects …