A decade after environmental scientists integrated high‐throughput sequencing
technologies in their toolbox, the genomics‐based monitoring of anthropogenic impacts on …

Next generation sequencing is in the process of evolving from a technology used for
research purposes to one which is applied in clinical diagnostics. Recently introduced high …

Background Improving survival and extending the longevity of life for all populations
requires timely, robust evidence on local mortality levels and trends. The Global Burden of …

In clinical exome and genome sequencing, there is a potential for the recognition and
reporting of incidental or secondary findings unrelated to the indication for ordering the …

Abstract The Electronic Medical Records and Genomics Network is a National Human
Genome Research Institute–funded consortium engaged in the development of methods …

The foundation for a new era of data-driven medicine has been set by recent technological
advances that enable the assessment and management of human health at an …

Genome-wide association studies (GWASs) have been heralded as a major advance in
biomedical discovery, having identified~ 2,000 robust associations with complex diseases …

We are experiencing a revolution in cancer. Advances in screening, targeted and immune
therapies, big data, computational methodologies, and significant new knowledge of cancer …

Clinical implementation of pharmacogenomics (PGx) leads to personalized medicine, which
improves the efficacy, safety, and cost-effectiveness of treatments. Although PGx-based …

Background The approach to the diagnosis of severe combined immunodeficiency disease
(SCID) and related disorders varies among institutions and countries. Objectives The …