Massive trauma remains a leading cause of death and a global public health burden. Post-
traumatic coagulopathy may be present even before the onset of resuscitation, and …

Background Cardiovascular disease is a major cause of morbidity and mortality in COPD.
Endothelial dysfunction is suggested to be one of the pathogenetic mechanisms involved …

Endothelial dysfunction, prevalent in cardiovascular diseases (CVDs) and linked to
conditions like diabetes, hypertension, obesity, renal failure, or hypercholesterolemia, is …

Although it is well-known that sex and age are important factors regulating endothelial cell
(EC) function, the impact of sex and age on the gene expression of ECs has not been …

Exposure to hypoxia elicits widespread physiological responses that are critical for
successful acclimatization; however, these responses may induce apparent maladaptive …

In keeping with the extraordinary interest and advancement of extracellular vesicles (EVs) in
pathogenesis and diagnosis fields, we herein present an update to the knowledge about …

Arterial endothelial function is acutely and chronically regulated by blood flow-associated
shear stress. An acute intervention employing modest forearm cuff occlusion to …

Acutely imposed oscillatory shear stress (OSS) reduces reactive hyperemia flow-mediated
dilation (RH-FMD) in conduit arteries of men; however, whether a similar impairment occurs …

Hemodynamic shear stress (SS), a frictional force generated by blood flow, regulates
vascular homeostasis. High and steady SS maintains physiological function of endothelial …

The pathogenesis of chronic obstructive pulmonary disease (COPD) is characterized by
complex cellular and molecular mechanisms, not fully elucidated so far. It involves …