[HTML][HTML] New insights into the circadian rhythm and its related diseases

Y Xie, Q Tang, G Chen, M Xie, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Glucocorticoid-induced osteoporosis

B Frenkel, W White, J Tuckermann - … Signaling: From Molecules to Mice to …, 2015 - Springer
Osteoporosis is among the most devastating side effects of glucocorticoid (GC) therapy for
the management of inflammatory and auto-immune diseases. Evidence from both humans …

Stromal stem cells from adipose tissue and bone marrow of age‐matched female donors display distinct immunophenotypic profiles

G Pachón‐Peña, G Yu, A Tucker, X Wu… - Journal of cellular …, 2011 - Wiley Online Library
Adipose tissue is composed of lipid‐filled mature adipocytes and a heterogeneous stromal
vascular fraction (SVF) population of cells. Similarly, the bone marrow (BM) is composed of …

Injectable PLGA based colloidal gels for zero-order dexamethasone release in cranial defects

Q Wang, J Wang, Q Lu, MS Detamore, C Berkland - Biomaterials, 2010 - Elsevier
Bone fillers have emerged as an alternative to the invasive surgery often required to repair
skeletal defects. Achieving controlled release from these materials is desired for …

Age‐related changes in mesenchymal stem cells derived from rhesus macaque bone marrow

JM Yu, X Wu, JM Gimble, X Guan, MA Freitas… - Aging cell, 2011 - Wiley Online Library
The regeneration potential of mesenchymal stem cells (MSCs) diminishes with advanced
age and this diminished potential is associated with changes in cellular functions. This study …

[HTML][HTML] Stem cells and the circadian clock

M Weger, N Diotel, AC Dorsemans, T Dickmeis… - Developmental …, 2017 - Elsevier
The circadian timing system is a complex biological network of interacting circadian clocks
that regulates 24 h rhythms of behavioral and physiological processes. One intriguing …

Circadian rhythms influence hematopoietic stem cells

S Méndez-Ferrer, A Chow, M Merad… - Current opinion in …, 2009 - journals.lww.com
Circadian rhythms influence hematopoietic stem cells : Current Opinion in Hematology
Circadian rhythms influence hematopoietic stem cells : Current Opinion in Hematology Log in …

Insights into the role of circadian rhythms in bone metabolism: a promising intervention target?

C Song, J Wang, B Kim, C Lu, Z Zhang… - BioMed research …, 2018 - Wiley Online Library
Numerous physiological processes of mammals, including bone metabolism, are regulated
by the circadian clock system, which consists of a central regulator, the suprachiasmatic …

Culture effects of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) on cryopreserved human adipose‐derived stromal/stem cell proliferation and …

TL Hebert, X Wu, G Yu, BC Goh… - Journal of tissue …, 2009 - Wiley Online Library
Previous studies have demonstrated that EGF and bFGF maintain the stem cell properties of
proliferating human adipose‐derived stromal/stem cells (hASCs) in vitro. While the …

[HTML][HTML] The Clock Genes Period 2 and Cryptochrome 2 Differentially Balance Bone Formation

E Maronde, AF Schilling, S Seitz, T Schinke, I Schmutz… - PloS one, 2010 - journals.plos.org
Background Clock genes and their protein products regulate circadian rhythms in mammals
but have also been implicated in various physiological processes, including bone formation …