The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

In contrast to almost all other brain tumors, diffuse gliomas infiltrate extensively in the
neuropil. This growth pattern is a major factor in therapeutic failure. Diffuse infiltrative glioma …

TWEAK is a multifunctional cytokine that controls many cellular activities including
proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK …

Simple Summary Although conventional anti-cancer drugs have been the footstone in the
fight against cancer, yet they are far from optimal due to issues related with indiscriminate …

First described as a weak apoptosis inducer, the TNF superfamily ligand TWEAK has since
emerged as a cytokine that regulates multiple cellular responses, including proinflammatory …

Abstract Glycogen synthase kinase 3 (GSK3), a serine/threonine kinase, is involved in
diverse cellular processes ranging from nutrient and energy homeostasis to proliferation and …

TWEAK (tumor necrosis factor–related weak inducer of apoptosis), a member of the tumor
necrosis factor superfamily, acts on cells by binding to its only receptor named Fn14 …

Glioblastoma is a highly aggressive brain tumor that is characterized by its unparalleled
invasiveness. Invasive glioblastoma cells not only escape surgery and focal therapies but …

Nuclear factor-κB (NF-κB) is a ubiquitous transcription factor that regulates multiple aspects
of cancer formation, growth, and treatment response. Glioblastoma (GBM), the most common …

TWEAK (TNF-like weak inducer of apoptosis) is a TNF superfamily member implicated in
several mechanisms. Although fibroblast growth factor inducible 14 (Fn14)/TweakR has …