Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Methionine uptake and metabolism is involved in a host of cellular functions including
methylation reactions, redox maintenance, polyamine synthesis and coupling to folate …

Nutrition exerts considerable effects on health, and dietary interventions are commonly used
to treat diseases of metabolic aetiology. Although cancer has a substantial metabolic …

Protein-restricted diets promote health and longevity in many species. While the precise
components of a protein-restricted diet that mediate the beneficial effects to longevity have …

The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell
growth that responds to a diverse set of environmental inputs, including amino acids. Over …

Dietary restriction (DR) without malnutrition encompasses numerous regimens with
overlapping benefits including longevity and stress resistance, but unifying nutritional and …

Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Age-associated changes in mitochondria are closely involved in aging. Apart from the
established roles in bioenergetics and biosynthesis, mitochondria are signaling organelles …

Bees acquire carbohydrates from nectar and lipids; and amino acids from pollen, which also
contains polysaccharides including cellulose, hemicellulose, and pectin. These potential …

The workshop entitled 'Interventions to Slow Aging in Humans: Are We Ready?'was held in
Erice, Italy, on October 8–13, 2013, to bring together leading experts in the biology and …