The role of microRNAs in neurodegenerative diseases: a review

S Li, Z Lei, T Sun - Cell Biology and Toxicology, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …

Regulation of microRNA function in somatic stem cell proliferation and differentiation

A Shenoy, RH Blelloch - Nature reviews Molecular cell biology, 2014 - nature.com
Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

MicroRNAs in neural development: from master regulators to fine-tuners

M Rajman, G Schratt - Development, 2017 - journals.biologists.com
The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …

miR-9: a versatile regulator of neurogenesis

M Coolen, S Katz, L Bally-Cuif - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Soon after its discovery, microRNA-9 (miR-9) attracted the attention of neurobiologists, since
it is one of the most highly expressed microRNAs in the developing and adult vertebrate …

MicroRNAs as regulators of brain function and targets for treatment of epilepsy

GP Brennan, DC Henshall - Nature Reviews Neurology, 2020 - nature.com
Seizures result from hypersynchronous, abnormal firing of neuronal populations and are the
primary clinical symptom of the epilepsies. Brain tissue from animal models and patients …

[HTML][HTML] MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

E Sun, Y Shi - Experimental neurology, 2015 - Elsevier
MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that play important
roles in the development and functions of the brain. Extensive studies have revealed critical …

microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons

F Dajas-Bailador, B Bonev, P Garcez, P Stanley… - Nature …, 2012 - nature.com
The capacity of neurons to develop a long axon and multiple dendrites defines neuron
connectivity in the CNS. The highly conserved microRNA-9 (miR-9) is expressed in both …

Neural stem cell-derived exosomes regulate neural stem cell differentiation through miR-9-Hes1 axis

P Yuan, L Ding, H Chen, Y Wang, C Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Exosomes, a key element of the central nervous system microenvironment, mediate
intercellular communication via horizontally transferring bioactive molecules. Emerging …

A critical evaluation of neuroprotective and neurodegenerative MicroRNAs in Alzheimer's disease

PH Reddy, S Tonk, S Kumar, M Vijayan… - Biochemical and …, 2017 - Elsevier
Abstract Currently, 5.4 million Americans suffer from AD, and these numbers are expected to
increase up to 16 million by 2050. Despite tremendous research efforts, we still do not have …

MicroRNA-9: functional evolution of a conserved small regulatory RNA

Y Yuva-Aydemir, A Simkin, E Gascon, FB Gao - RNA biology, 2011 - Taylor & Francis
The functional significance of microRNA-9 (miR-9) during evolution is evidenced by its
conservation at the nucleotide level from flies to humans but not its diverse expression …