The emerging role of GSNOR in oxidative stress regulation

B Li, C Sun, X Lin, W Busch - Trends in plant science, 2021 - cell.com
Oxidative stress is a common event in aerobic organisms and a fundamental and
unavoidable cost of the aerobic lifestyle. Reactive oxygen and nitrogen species (ROS/RNS) …

Nitric oxide and S-nitrosylation in cardiac regulation: G protein-coupled receptor kinase-2 and β-arrestins as targets

G Kayki-Mutlu, WJ Koch - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiac diseases including heart failure (HF), are the leading cause of morbidity and
mortality globally. Among the prominent characteristics of HF is the loss of β-adrenoceptor …

Nitrosative Stress in Astronaut Skeletal Muscle in Spaceflight

D Blottner, M Moriggi, G Trautmann, S Furlan, K Block… - Antioxidants, 2024 - mdpi.com
Long-duration mission (LDM) astronauts from the International Space Station (ISS)(> 180
ISS days) revealed a close-to-normal sarcolemmal nitric oxide synthase type-1 (NOS1) …

When S-Nitrosylation Gets to Mitochondria: From Signaling to Age-Related Diseases

C Montagna, C Cirotti, S Rizza… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Cysteines have an essential role in redox signaling, transforming an oxidant
signal into a biological response. Among reversible cysteine post-translational …

The interplay between mitochondrial functionality and genome integrity in the prevention of human neurologic diseases

M D'Errico, E Parlanti, B Pascucci, G Filomeni… - Archives of Biochemistry …, 2021 - Elsevier
As mitochondria are vulnerable to oxidative damage and represent the main source of
reactive oxygen species (ROS), they are considered key tuners of ROS metabolism and …

Autophagy guards tendon homeostasis

C Montagna, RB Svensson, ML Bayer, S Rizza… - Cell death & …, 2022 - nature.com
Tendons are vital collagen-dense specialized connective tissues transducing the force from
skeletal muscle to the bone, thus enabling movement of the human body. Tendon cells …

Transcriptomic investigation of embryonic pectoral muscle reveals increased myogenic processes in Shitou geese compared to Wuzong geese

X Zhang, J Wang, X Li, X Shen, D Xu, Y Tian… - British Poultry …, 2021 - Taylor & Francis
Embryonic stages before birth are crucial for poultry muscle development, as this determines
muscle mass in adulthood. This study characterised the distinction in embryonic pectoral …

[HTML][HTML] The role of S-nitrosoglutathione reductase (GSNOR) in T cell-mediated immunopathology of experimental autoimmune encephalomyelitis (EAE)

I Singh, J Kim, SMT Islam, Q Fei, AK Singh, J Won - Neuroscience, 2025 - Elsevier
Previously, we reported that both S-nitrosoglutathione (GSNO), a carrier of cellular nitric
oxide, and N6022, an injectable form of GSNO reductase (GSNOR) inhibitor that increases …

Expression of neuronal NO synthase α-and β-isoforms in skeletal muscle of mice

O Baum - Biochemical Journal, 2024 - portlandpress.com
Knowledge of the primary structure of neuronal NO synthase (nNOS) in skeletal muscle is
still conflicting and needs further clarification. To elucidate the expression patterns of nNOS …

Hormonal, immune, and oxidative stress responses to blood flow‐restricted exercise

MH Hjortshoej, P Aagaard, CD Storgaard… - Acta …, 2023 - Wiley Online Library
Introduction Heavy‐load free‐flow resistance exercise (HL‐FFRE) is a widely used training
modality. Recently, low‐load blood‐flow restricted resistance exercise (LL‐BFRRE) has …