Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Traumatic brain injury (TBI) is one of the leading causes of death of young people in the
developed world. In the United States alone, 1.7 million traumatic events occur annually …

Introduction: For half a century, a high level of total cholesterol (TC) or low-density
lipoprotein cholesterol (LDL-C) has been considered to be the major cause of …

ABSTRACT BACKGROUND In 2012, the United States Food and Drug Administration (FDA)
issued a warning regarding potential adverse effects of HMG-CoA reductase inhibitors …

The objective of this scientific statement is to evaluate contemporary evidence that either
supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol …

Oxidative stress is a key player in both chronic and acute brain disease due to the higher
metabolic demand of the brain. Among the producers of free radicals, NADPH-oxidase …

In the last 50 years, several clinical and epidemiological studies during have shown that
increased levels of low-density lipoprotein cholesterol (LDLc) are associated with the …

Abstract The National Lipid Association's Safety Task Force convened a consensus
conference of experts to develop a position statement on cognitive function to revise and …

We have provided a critical assessment of research on the reduction of cholesterol levels by
statin treatment to reduce cardiovascular disease. Our opinion is that although statins are …

Statins are more widely used not only for the primary and secondary prevention of
cardiovascular disease by blocking cholesterol biosynthesis but also for the potential …