The mouse small intestine shows profound variability in gene expression along the crypt–
villus axis,. Whether similar spatial heterogeneity exists in the adult human gut remains …

Bariatric surgical procedures such as sleeve gastrectomy (SG) provide effective type 2
diabetes (T2D) remission in human patients. Previous work demonstrated that …

Neutrophilic inflammation contributes to multiple chronic inflammatory airway diseases,
including asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), and is associated …

The recent development of single-cell transcriptomics highlighted the existence of a new
lineage of mature absorptive cells in the human intestinal epithelium. This subpopulation is …

Primary sclerosing cholangitis (PSC) is characterized by abnormal bile acid metabolites and
altered gut microbiota, with no effective treatments available. Vancomycin, a glycopeptide …

This study aimed to investigate the effects of dietary corn-resistant starch on the bile acid
metabolism of broilers. In total, 80, 1-day-old male broilers were randomly distributed into …

Artificial intelligence (AI)-driven discovery of antimicrobial peptides (AMPs) is yet to fully
utilise their three-dimensional (3D) structural characteristics, microbial specie-specific …