Continuous manufacturing and molecular modeling of pharmaceutical amorphous solid dispersions

AG Nambiar, M Singh, AR Mali, DR Serrano… - AAPS …, 2022 - Springer
Amorphous solid dispersions enhance solubility and oral bioavailability of poorly water-
soluble drugs. The escalating number of drugs with poor aqueous solubility, poor …

Solubility improvement of curcumin by crystallization inhibition from polymeric surfactants in amorphous solid dispersions

Z Xi, Y Fei, Y Wang, Q Lin, Q Ke, G Feng… - Journal of Drug Delivery …, 2023 - Elsevier
To improve the solubility and maintain amorphous state of curcumin (CUR), solid
dispersions of CUR with Kollidon CLSF and surfactant (TPGS or HPMC) were prepared by …

Development of a bilayer tablet by fused deposition modeling as a sustained-release drug delivery system

AG Crișan, A Porfire, S Iurian, LM Rus… - Pharmaceuticals, 2023 - mdpi.com
Three-dimensional printing by fused deposition modeling (FDM) coupled with hot-melt
extrusion (HME) is a point of convergence of research efforts directed toward the …

Kollidon® SR: Formulation techniques and drug delivery applications

SA Rahim, N Al-Zoubi, S Gharaibeh… - International Journal of …, 2024 - Elsevier
Kollidon® SR is one of the recent versatile coprocessed excipients in the formulation of
modified release dosage forms. It is prepared by co-spray drying from aqueous dispersions …

Leveraging solid solubility and miscibility of etoricoxib in Soluplus® towards manufacturing of 3D printed etoricoxib tablets by additive manufacturing

MK Ashokbhai, S Ghatole, U Gupta, LR Sanjay… - International Journal of …, 2024 - Elsevier
This research focuses on exploring the solid solubility and miscibility of Etoricoxib, a poorly
water-soluble anti-inflammatory drug, within Soluplus®, a polymer used as a matrix for 3D …

Customized 3D-printed hollow capsular device filled with norfloxacin-loaded micropellets for controlled-release delivery

P Suryavanshi, VS Chaudhari, S Banerjee - Drug Delivery and …, 2023 - Springer
Pharmacotherapy has become more focused on the personalized treatment of patients with
various diseases. This field of pharmacology and pharmacogenomics focuses on …

Comparative Life Cycle Assessment and Pharmaceutical Validations of Directly Compressed versus Additively Manufactured Tablets

T Gharate, T Karanwad, MK Deka… - Industrial & …, 2024 - ACS Publications
Selective laser sintering (SLS)-mediated additive manufacturing (AM) technology is
increasingly being used for manufacturing pharmaceutical solid oral dosage forms (SODFs) …

3D printed tinidazole tablets coupled with melt-extrusion techniques for formulating child friendly medicines

A Pawar, T Karanwad, S Banerjee - European Journal of Pharmaceutics …, 2024 - Elsevier
This study investigates the feasibility of fabrication of poly (1-vinyl-2-pyrrolidone)(Kollidon®
25)-mediated filaments for producing tinidazole (TNZ)-loaded, customizable, child-friendly …

Selection of appropriate dapsone and poly (1-vinylpyrrolidone-co-vinyl acetate) ratios for the preparation of amorphous solid dispersions

D Choudhury, US Murty, S Banerjee - Heliyon, 2023 - cell.com
Drug-polymer miscibility is a critical requirement for the efficient design and development of
amorphous solid dispersions. The objective of the current study was to determine the …

Systematic evaluations of melt-extruded filament for fused deposition modeling-mediated 3D printing

U Bhatt, PK Sharma, US Murty… - Journal of 3D Printing in …, 2022 - Taylor & Francis
Aim: The significant critical barrier in the ascension of fused deposition modeling (FDM) into
a scalable technology is the lack of defined quality benchmarks for validating filament …