Research on matrix metalloproteinases (MMPs) and in particular on gelatinase B, alias MMP-
9, has grown exponentially in the decade 2003–2012. Structural details about flexibility of …

Matrix metalloproteinases (MMPs) have outgrown the field of extracellular-matrix biology
and have progressed towards being important regulatory molecules in cancer and …

The endothelial cell monolayer of cerebral vessels and its basement membrane (BM) are
ensheathed by the astrocyte endfeet, the leptomeningeal cells, and their associated …

The matrix metalloproteinases (MMPs), a family of 25 secreted and cell surface-bound
neutral proteinases, process a large array of extracellular and cell surface proteins under …

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that have
been increasingly linked to both normal physiology and abnormal pathology in the kidney …

The mechanisms by which IL-6 contributes to the pathogenesis of chronic inflammatory
diseases and cancer are not fully understood. We previously reported that cyclooxygenase …

Familial amyloidotic polyneuropathy is an autosomal dominant disorder mainly
characterized by the extracellular deposition of transthyretin, with special involvement of the …

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases with important roles
in kidney homeostasis and pathology. While capable of collectively degrading each …

Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after
lung transplantation. CLAD manifests as bronchiolitis obliterans syndrome (BOS) or …

Proteases play an important role in health and disease of the lung. In the normal lungs,
proteases maintain their homeostatic functions that regulate processes like its regeneration …