Caffeic acid and its derivatives: antimicrobial drugs toward microbial pathogens

F Khan, NI Bamunuarachchi… - Journal of agricultural …, 2021 - ACS Publications
Caffeic acid is a plant-derived compound that is classified as hydroxycinnamic acid which
contains both phenolic and acrylic functional groups. Caffeic acid has been greatly …

An overview on the synthetic urease inhibitors with structure-activity relationship and molecular docking

W Yang, Q Feng, Z Peng, G Wang - European Journal of Medicinal …, 2022 - Elsevier
Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …

Chlorogenic acid prevents hepatotoxicity in arsenic-treated mice: role of oxidative stress and apoptosis

MA Dkhil, AE Abdel Moneim, AA Bauomy… - Molecular biology …, 2020 - Springer
Arsenic is a potent and toxic heavy metal found in the environment that causes health
problems, including liver disease, in humans and animals. Chlorogenic acid (CA) is the most …

Nephroprotective effects of chlorogenic acid against sodium arsenite‐induced oxidative stress, inflammation, and apoptosis

WA AL‐Megrin, DM Metwally… - Journal of the …, 2020 - Wiley Online Library
BACKGROUND Chronic exposure to arsenic (As) leads to serious renal disorders.
Chlorogenic acid (CGA), a phenolic compound, has several well known physiological …

Recovery of chlorogenic acid from the DES-based extract of Eucommia ulmoides leaves by molecularly imprinted solid-phase extraction

Z Liu, W Ma, B Chen, H Pan, H Wu, Q Zhang - Industrial Crops and …, 2023 - Elsevier
To develop new ideas about the recovery of target components from the deep eutectic
solvent (DES)-based extract, molecularly imprinted polymers (MIPs) were adopted as fillers …

Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review

S Joneidi, SR Alizadeh… - Mini Reviews in …, 2024 - ingentaconnect.com
Background: Phenolic acids have recently gained considerable attention because of their
numerous practical, biological, and pharmacological benefits. Various polyphenolic …

Structure-based designing, solvent less synthesis of 1, 2, 3, 4-tetrahydropyrimidine-5-carboxylate derivatives: A combined in vitro and in silico screening approach

U Arshad, S Ahmed, N Shafiq, Z Ahmad, A Hassan… - Molecules, 2021 - mdpi.com
Objective: In this study, small molecules possessing tetrahydropyrimidine derivatives have
been synthesized having halogenated benzyl derivatives and carboxylate linkage. As …

Phytochemical profiling, antioxidant activities and in vitro/in silico enzyme inhibitory potentials of apricot cultivars grown in Iğdır/Turkey

AA Karaçelik - South African Journal of Botany, 2023 - Elsevier
Phenolic profile, total phenolic content (TPC), antioxidant activity and carbonic anhydrase
(CA) and urease inhibition potentials of fresh and dried fruit extracts of four main apricot …

Terpenoid and Fatty Acid Profiling along with Anti‐Tyrosinase and Anti‐Urease Potentials of Scorzonera pygmaea Sibth. & Sm. an Endemic Plant of Turkey

H Şahin, M Boğa, A Sarı - Chemistry & Biodiversity, 2022 - Wiley Online Library
Abstract Petroleum ether (PE), chloroform (CH), ethyl acetate (EA) and butanol (BU)
fractions were obtained from ethanol extracts of the roots (SPR) and the above ground …

One-pot multicomponent synthesis of novel pyridine derivatives for antidiabetic and antiproliferative activities

N Shafiq, N Shahzad, F Rida, Z Ahmad… - Future Medicinal …, 2023 - Taylor & Francis
Background: Due to the close relationship of diabetes with hypertension reported in various
research, a set of pyridine derivatives with US FDA-approved drug cores were designed and …