Controlled drug delivery vehicles for cancer treatment and their performance

S Senapati, AK Mahanta, S Kumar… - Signal transduction and …, 2018 - nature.com
Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Tailoring the Swelling‐Shrinkable Behavior of Hydrogels for Biomedical Applications

W Feng, Z Wang - Advanced Science, 2023 - Wiley Online Library
Hydrogels with tailor‐made swelling‐shrinkable properties have aroused considerable
interest in numerous biomedical domains. For example, as swelling is a key issue for blood …

Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications

JG Croissant, Y Fatieiev, A Almalik… - Advanced healthcare …, 2018 - Wiley Online Library
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …

Gated materials for on-command release of guest molecules

E Aznar, M Oroval, L Pascual, JR Murguía… - Chemical …, 2016 - ACS Publications
Multidisciplinary research at the forefront of the field of hybrid materials has paved the way to
the development of endless examples of smart devices. One appealing concept in this fertile …

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

N Kamaly, Z Xiao, PM Valencia… - Chemical Society …, 2012 - pubs.rsc.org
Polymeric materials have been used in a range of pharmaceutical and biotechnology
products for more than 40 years. These materials have evolved from their earlier use as …

Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation

X Wang, J Zhang, Y Wang, C Wang, J Xiao, Q Zhang… - Biomaterials, 2016 - Elsevier
Abstract Photothermal-chemotherapy (PT-CT) is a promising strategy for cancer treatment,
but its development is hindered by the issues regarding to the long-term safety of carriers …

Functionalized mesoporous silica materials for controlled drug delivery

P Yang, S Gai, J Lin - Chemical Society Reviews, 2012 - pubs.rsc.org
In the past decade, non-invasive and biocompatible mesoporous silica materials as efficient
drug delivery systems have attracted special attention. Great progress in structure control …

Mesoporous silica nanoparticles for stimuli-responsive controlled drug delivery: advances, challenges, and outlook

Y Song, Y Li, Q Xu, Z Liu - International journal of nanomedicine, 2017 - Taylor & Francis
With the development of nanotechnology, the application of nanomaterials in the field of
drug delivery has attracted much attention in the past decades. Mesoporous silica …

Drug release from electric-field-responsive nanoparticles

J Ge, E Neofytou, TJ Cahill III, RE Beygui, RN Zare - ACS nano, 2012 - ACS Publications
We describe a new temperature and electric field dual-stimulus responsive nanoparticle
system for programmed drug delivery. Nanoparticles of a conducting polymer (polypyrrole) …